# Nuclear factor kappa B subunit 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q4044834](https://www.wikidata.org/wiki/Q4044834)  
**Source**: https://4ort.xyz/entity/nuclear-factor-kappa-b-subunit-1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P19838)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19838)
5. [HMGA2 regulates transcription of the Imp2 gene via an intronic regulatory element in cooperation with nuclear factor-kappaB](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19838)
6. [NF-kappa B and C/EBP transcription factor families synergistically function in mouse serum amyloid A gene expression induced by inflammatory cytokines](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19838)
7. [Prostaglandin E receptor type 4-associated protein interacts directly with NF-kappaB1 and attenuates macrophage activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19838)
8. [Selection of optimal kappa B/Rel DNA-binding motifs: interaction of both subunits of NF-kappa B with DNA is required for transcriptional activation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P19838&geneProductId=UniProtKB:P19838)
9. [Selection of optimal kappa B/Rel DNA-binding motifs: interaction of both subunits of NF-kappa B with DNA is required for transcriptional activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19838)
10. [Ankrd2 is a modulator of NF-κB-mediated inflammatory responses during muscle differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19838)
11. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P19838&geneProductId=UniProtKB:P19838)
12. [Identification of a novel protein from glial cells based on its ability to interact with NF‐κB subunitsr](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19838)
13. [Physical interaction of the bHLH LYL1 protein and NF-kappaB1 p105](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19838)
14. [Stimulation of CD30 in anaplastic large cell lymphoma leads to production of nuclear factor-kappaB p52, which is associated with hyperphosphorylated Bcl-3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19838)
15. [The tumor suppressor protein menin interacts with NF-kappaB proteins and inhibits NF-kappaB-mediated transactivation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19838)
16. [Dimerization of NF-KB2 with RelA(p65) regulates DNA binding, transcriptional activation, and inhibition by an I kappa B-alpha (MAD-3)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19838)
17. [BCL3 encodes a nuclear protein which can alter the subcellular location of NF-kappa B proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19838)
18. [Respiratory syncytial virus-inducible BCL-3 expression antagonizes the STAT/IRF and NF-kappaB signaling pathways by inducing histone deacetylase 1 recruitment to the interleukin-8 promoter](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19838)
19. [Posttranslational hydroxylation of ankyrin repeats in IkappaB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19838)
20. [A human interactome in three quantitative dimensions organized by stoichiometries and abundances](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19838)
21. [Herpes simplex virus 1 DNA polymerase processivity factor UL42 inhibits TNF-α-induced NF-κB activation by interacting with p65/RelA and p50/NF-κB1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19838)
22. [Notch1 augments NF-kappaB activity by facilitating its nuclear retention](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19838)
23. [The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19838)
24. [LRP16 Integrates into NF-κB Transcriptional Complex and Is Required for Its Functional Activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19838)
25. [Structure of an IkappaBalpha/NF-kappaB complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19838)
26. [A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19838)
27. [Ribosomal protein S3: a KH domain subunit in NF-kappaB complexes that mediates selective gene regulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19838)
28. [Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19838)
29. [A Comprehensive Resource of Interacting Protein Regions for Refining Human Transcription Factor Networks](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19838)
30. [betaTrCP-mediated proteolysis of NF-kappaB1 p105 requires phosphorylation of p105 serines 927 and 932.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19838)
31. [NF-kappaB1 p105 negatively regulates TPL-2 MEK kinase activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19838)
32. [Using an in Situ Proximity Ligation Assay to Systematically Profile Endogenous Protein–Protein Interactions in a Pathway Network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19838)
33. [Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19838)
34. [Direct phosphorylation of NF-kappaB1 p105 by the IkappaB kinase complex on serine 927 is essential for signal-induced p105 proteolysis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19838)
35. [NF-kappaB subunit p65 binds to 53BP2 and inhibits cell death induced by 53BP2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19838)
36. [The RNA aptamer disrupts protein-protein interaction between beta-catenin and nuclear factor-kappaB p50 and regulates the expression of C-reactive protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19838)
37. [Zinc finger protein Gfi1 controls the endotoxin-mediated Toll-like receptor inflammatory response by antagonizing NF-kappaB p65](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19838)
38. [Toward an understanding of the protein interaction network of the human liver](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19838)
39. [COMMD proteins, a novel family of structural and functional homologs of MURR1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19838)
40. [Annexin A4 interacts with the NF-kappaB p50 subunit and modulates NF-kappaB transcriptional activity in a Ca2+-dependent manner](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19838)
41. [α-Actinin 4 potentiates nuclear factor κ-light-chain-enhancer of activated B-cell (NF-κB) activity in podocytes independent of its cytoplasmic actin binding function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19838)
42. [Epigenetic regulation of HYAL-1 hyaluronidase expression. identification of HYAL-1 promoter](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19838)
43. [Copine-I represses NF-kappaB transcription by endoproteolysis of p65](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19838)
44. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19838)
45. [Expression of nuclear factor-kappa B in hepatocellular carcinoma and its relation with the X protein of hepatitis B virus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19838)
46. [Cloning of the DNA-binding subunit of human nuclear factor kappa B: the level of its mRNA is strongly regulated by phorbol ester or tumor necrosis factor alpha](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19838)
47. [Macrophage-specific inhibition of NF-kappaB activation reduces foam-cell formation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19838)
48. [MicroRNA-21 blocks abdominal aortic aneurysm development and nicotine-augmented expansion](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19838)
49. [Type I collagen promotes epithelial-mesenchymal transition through ILK-dependent activation of NF-kappaB and LEF-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19838)
50. [Down-regulation by nuclear factor kappaB of human 25-hydroxyvitamin D3 1alpha-hydroxylase promoter](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19838)