# Nuclear factor, erythroid 2 like 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21119958](https://www.wikidata.org/wiki/Q21119958)  
**Source**: https://4ort.xyz/entity/nuclear-factor-erythroid-2-like-1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q14494)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14494)
5. [Cloning of Nrf1, an NF-E2-related transcription factor, by genetic selection in yeast](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14494&geneProductId=UniProtKB:Q14494)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14494&geneProductId=UniProtKB:Q14494)
7. [Nrf1 in a complex with fosB, c-jun, junD and ATF2 forms the AP1 component at the TNF alpha promoter in stimulated mast cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14494)
8. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14494)
9. [Identification of bZIP interaction partners of viral proteins HBZ, MEQ, BZLF1, and K-bZIP using coiled-coil arrays](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14494)
10. [Interaction of the CNC-bZIP factor TCF11/LCR-F1/Nrf1 with MafG: Binding-site selection and regulation of transcription](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14494&geneProductId=UniProtKB:Q14494)
11. [Small Maf proteins interact with the human transcription factor TCF11/Nrf1/LCR-F1](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14494&geneProductId=UniProtKB:Q14494)
12. [TCF11/Nrf1 overexpression increases the intracellular glutathione level and can transactivate the gamma-glutamylcysteine synthetase (GCS) heavy subunit promoter](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14494&geneProductId=UniProtKB:Q14494)
13. [The CNC basic leucine zipper factor, Nrf1, is essential for cell survival in response to oxidative stress-inducing agents. Role for Nrf1 in gamma-gcs(l) and gss expression in mouse fibroblasts](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14494&geneProductId=UniProtKB:Q14494)
14. [NF-E2-related factor 1 (Nrf1) serves as a novel regulator of hepatic lipid metabolism through regulation of the Lipin1 and PGC-1β genes](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14494&geneProductId=UniProtKB:Q14494)
15. [Transcription factor Nrf1 mediates the proteasome recovery pathway after proteasome inhibition in mammalian cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14494&geneProductId=UniProtKB:Q14494)
16. [The CCAAT enhancer-binding protein (C/EBP)beta and Nrf1 interact to regulate dentin sialophosphoprotein (DSPP) gene expression during odontoblast differentiation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14494&geneProductId=UniProtKB:Q14494)
17. [NRF1 Is an ER Membrane Sensor that Is Central to Cholesterol Homeostasis.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14494&geneProductId=UniProtKB:Q14494)
18. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14494)
19. [Cloning of Nrf1, an NF-E2-related transcription factor, by genetic selection in yeast](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14494)
20. [p97-dependent retrotranslocation and proteolytic processing govern formation of active Nrf1 upon proteasome inhibition](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14494&geneProductId=UniProtKB:Q14494)
21. [The aspartyl protease DDI2 activates Nrf1 to compensate for proteasome dysfunction](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14494&geneProductId=UniProtKB:Q14494)
22. [Targeted disruption of the ubiquitous CNC-bZIP transcription factor, Nrf-1, results in anemia and embryonic lethality in mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14494)
23. [Nrf1 in a complex with fosB, c-jun, junD and ATF2 forms the AP1 component at the TNF alpha promoter in stimulated mast cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14494&geneProductId=UniProtKB:Q14494)
24. Ensembl Release 99
25. UMLS 2023