# Notch 2

> mammalian protein found in Mus musculus

**Wikidata**: [Q21986192](https://www.wikidata.org/wiki/Q21986192)  
**Source**: https://4ort.xyz/entity/notch-2-q21986192


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O35516)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35516)
5. [The association of Notch2 and NF-kappaB accelerates RANKL-induced osteoclastogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35516)
6. [Mouse jagged1 physically interacts with notch2 and other notch receptors. Assessment by quantitative methods](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35516)
7. [Binding of Delta1, Jagged1, and Jagged2 to Notch2 rapidly induces cleavage, nuclear translocation, and hyperphosphorylation of Notch2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35516)
8. [Notch signaling in kidney development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35516)
9. [RBP-L, a transcription factor related to RBP-Jkappa](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35516)
10. [Asparaginyl hydroxylation of the Notch ankyrin repeat domain by factor inhibiting hypoxia-inducible factor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35516)
11. [Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35516)
12. [A role for the primary cilium in Notch signaling and epidermal differentiation during skin development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35516)
13. [Segmental expression of Notch and Hairy genes in nephrogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35516)
14. [Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35516)
15. [Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35516)
16. [Notch2 is required for formation of the placental circulatory system, but not for cell-type specification in the developing mouse placenta](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35516)
17. [Notch2-dependent classical dendritic cells orchestrate intestinal immunity to attaching-and-effacing bacterial pathogens](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35516)
18. [Notch2 regulates BMP signaling and epithelial morphogenesis in the ciliary body of the mouse eye](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35516)
19. [Lunatic and manic fringe cooperatively enhance marginal zone B cell precursor competition for delta-like 1 in splenic endothelial niches](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35516)
20. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O35516&geneProductId=UniProtKB:O35516)
21. [Notch signaling regulates left-right asymmetry determination by inducing Nodal expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35516)
22. [Notch1 and 2 cooperate in limb ectoderm to receive an early Jagged2 signal regulating interdigital apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35516)
23. [A mouse model of Alagille syndrome: Notch2 as a genetic modifier of Jag1 haploinsufficiency](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35516)
24. ensembl Release 106