# Notch 1

> mammalian protein found in Mus musculus

**Wikidata**: [Q21986193](https://www.wikidata.org/wiki/Q21986193)  
**Source**: https://4ort.xyz/entity/notch-1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q01705)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01705)
5. [Notch directly regulates Gata3 expression during T helper 2 cell differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01705)
6. [RBP-L, a transcription factor related to RBP-Jkappa](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01705)
7. [Notch4 reveals a novel mechanism regulating Notch signal transduction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01705)
8. [Asparaginyl hydroxylation of the Notch ankyrin repeat domain by factor inhibiting hypoxia-inducible factor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01705)
9. [Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01705)
10. [RBPjkappa-dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01705)
11. [Deciphering the Fringe-Mediated Notch Code: Identification of Activating and Inhibiting Sites Allowing Discrimination between Ligands](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01705)
12. [Mouse jagged1 physically interacts with notch2 and other notch receptors. Assessment by quantitative methods](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01705)
13. [The intracellular region of Notch ligands Dll1 and Dll3 regulates their trafficking and signaling activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01705)
14. [Consequences of MEGF10 deficiency on myoblast function and Notch1 interactions.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01705)
15. [Isolation and Functional Analysis of a cDNA for Human Jagged2, a Gene Encoding a Ligand for the Notch1 Receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01705)
16. [Cadherin-based adhesions in the apical endfoot are required for active Notch signaling to control neurogenesis in vertebrates](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01705)
17. [Delta-like 1-Lysine613 regulates notch signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01705)
18. [Binding of Delta1, Jagged1, and Jagged2 to Notch2 rapidly induces cleavage, nuclear translocation, and hyperphosphorylation of Notch2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01705)
19. [ZFP423 coordinates Notch and bone morphogenetic protein signaling, selectively up-regulating Hes5 gene expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01705)
20. [The nephroblastoma overexpressed gene (NOV/ccn3) protein associates with Notch1 extracellular domain and inhibits myoblast differentiation via Notch signaling pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01705)
21. [Fringe glycosyltransferases differentially modulate Notch1 proteolysis induced by Delta1 and Jagged1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01705)
22. [Pten coordinates retinal neurogenesis by regulating Notch signalling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01705)
23. [Baf60c is a nuclear Notch signaling component required for the establishment of left-right asymmetry](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01705)
24. [RITA, a novel modulator of Notch signalling, acts via nuclear export of RBP-J.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01705)
25. [Notch1 regulates the fate of cardiac progenitor cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01705)
26. [A protein (ORF2) encoded by the latency-related gene of bovine herpesvirus 1 interacts with Notch1 and Notch3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01705)
27. [Physical interaction between a novel domain of the receptor Notch and the transcription factor RBP-J kappa/Su(H)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01705)
28. [Notch signaling is essential for ventricular chamber development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01705)
29. [DNER acts as a neuron-specific Notch ligand during Bergmann glial development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01705)
30. [Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01705)
31. [Ascl1 (Mash1) Knockout Perturbs Differentiation of Nonneuronal Cells in Olfactory Epithelium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01705)
32. [Distinct roles for cell-autonomous Notch signaling in cardiomyocytes of the embryonic and adult heart](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01705)
33. [BMP7 inhibits branching morphogenesis in the prostate gland and interferes with Notch signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01705)
34. [Jag2-Notch1 signaling regulates oral epithelial differentiation and palate development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01705)
35. [Canonical notch signaling functions as a commitment switch in the epidermal lineage](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01705)
36. [A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01705)
37. [Monitoring Notch1 activity in development: evidence for a feedback regulatory loop](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01705)
38. [Endothelial nitric oxide signaling regulates Notch1 in aortic valve disease.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01705)
39. [Notch-Tnf signalling is required for development and homeostasis of arterial valves](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01705)
40. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01705)
41. [Differential Notch Signaling in the Epicardium Is Required for Cardiac Inflow Development and Coronary Vessel Morphogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01705)
42. [Artery and vein size is balanced by Notch and ephrin B2/EphB4 during angiogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01705)
43. [Notch signaling controls multiple steps of pancreatic differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01705)
44. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01705&geneProductId=UniProtKB:Q01705)
45. [Notch1 is required for the coordinate segmentation of somites](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01705)
46. [Segmental expression of Notch and Hairy genes in nephrogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01705)
47. [Hes1 but not Hes5 regulates an astrocyte versus oligodendrocyte fate choice in glial restricted precursors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01705)
48. [Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01705)
49. [Notch inhibition induces mitotically generated hair cells in mammalian cochleae via activating the Wnt pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01705)
50. [Integration of a Notch-dependent mesenchymal gene program and Bmp2-driven cell invasiveness regulates murine cardiac valve formation.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01705)