# Noggin

> mammalian protein found in Mus musculus

**Wikidata**: [Q22676651](https://www.wikidata.org/wiki/Q22676651)  
**Source**: https://4ort.xyz/entity/noggin-q22676651


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P97466)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97466)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97466&geneProductId=UniProtKB:P97466)
6. [Bone morphogenetic protein-2 can mediate myocardial regulation of atrioventricular cushion mesenchymal cell formation in mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97466&geneProductId=UniProtKB:P97466)
7. [Pelota regulates the development of extraembryonic endoderm through activation of bone morphogenetic protein (BMP) signaling](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97466&geneProductId=UniProtKB:P97466)
8. [Bone morphogenetic protein-2 can mediate myocardial regulation of atrioventricular cushion mesenchymal cell formation in mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97466)
9. [Pelota regulates the development of extraembryonic endoderm through activation of bone morphogenetic protein (BMP) signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97466)
10. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97466)
11. [Chordin and noggin promote organizing centers of forebrain development in the mouse](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97466)
12. [The BMP antagonist Noggin promotes cranial and spinal neurulation by distinct mechanisms](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97466)
13. [BMPs and BMP receptors in mouse metanephric development: in vivo and in vitro studies](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97466)
14. [The BMP Antagonists Chordin and Noggin Have Essential but Redundant Roles in Mouse Mandibular Outgrowth](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97466)
15. [Noggin regulates Bmp4 activity during pituitary induction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97466)
16. [Reduction of BMP4 activity by gremlin 1 enables ureteric bud outgrowth and GDNF/WNT11 feedback signalling during kidney branching morphogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97466)
17. [Regulation of skeletal progenitor differentiation by the BMP and retinoid signaling pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97466)
18. [Noggin is required for normal lobe patterning and ductal budding in the mouse prostate](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97466)
19. [Morphogenesis of the trachea and esophagus: current players and new roles for noggin and Bmps](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97466)
20. [ER71 acts downstream of BMP, Notch, and Wnt signaling in blood and vessel progenitor specification](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97466)
21. [Regulation of BMP-dependent chondrogenesis in early limb mesenchyme by TGFbeta signals](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97466)
22. [A potential role for bone morphogenetic protein signalling in glial cell fate determination following adult central nervous system injury in vivo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97466)
23. [Snorc is a novel cartilage specific small membrane proteoglycan expressed in differentiating and articular chondrocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97466)
24. [Noggin is required for correct guidance of dorsal root ganglion axons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97466)
25. [The BMP antagonist Noggin promotes cranial and spinal neurulation by distinct mechanisms](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97466&geneProductId=UniProtKB:P97466)
26. [A novel neural-specific BMP antagonist, Brorin-like, of the Chordin family](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97466&geneProductId=UniProtKB:P97466)
27. [A critical role for sFRP proteins in maintaining caudal neural tube closure in mice via inhibition of BMP signaling](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97466&geneProductId=UniProtKB:P97466)
28. [Repulsive guidance molecule (RGMa), a DRAGON homologue, is a bone morphogenetic protein co-receptor](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97466&geneProductId=UniProtKB:P97466)
29. [ER71 acts downstream of BMP, Notch, and Wnt signaling in blood and vessel progenitor specification](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97466&geneProductId=UniProtKB:P97466)
30. [Brorin, a novel secreted bone morphogenetic protein antagonist, promotes neurogenesis in mouse neural precursor cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97466&geneProductId=UniProtKB:P97466)
31. [The organizer factors Chordin and Noggin are required for mouse forebrain development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97466)
32. [Essential requirement of BMPs-2/4 for both osteoblast and osteoclast formation in murine bone marrow cultures from adult mice: antagonism by noggin](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97466&geneProductId=UniProtKB:P97466)
33. [Noggin-mediated antagonism of BMP signaling is required for growth and patterning of the neural tube and somite](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97466)
34. [The bone morphogenetic protein antagonist noggin regulates mammalian cardiac morphogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97466)
35. [Sox17 is essential for the specification of cardiac mesoderm in embryonic stem cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97466)
36. [Essential requirement of BMPs-2/4 for both osteoblast and osteoclast formation in murine bone marrow cultures from adult mice: antagonism by noggin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97466)
37. [A novel neural-specific BMP antagonist, Brorin-like, of the Chordin family](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97466)
38. [A critical role for sFRP proteins in maintaining caudal neural tube closure in mice via inhibition of BMP signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97466)
39. [Repulsive guidance molecule (RGMa), a DRAGON homologue, is a bone morphogenetic protein co-receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97466)
40. [Brorin, a novel secreted bone morphogenetic protein antagonist, promotes neurogenesis in mouse neural precursor cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97466)
41. ensembl Release 106