# Nodal

> mammalian protein found in Mus musculus

**Wikidata**: [Q22676929](https://www.wikidata.org/wiki/Q22676929)  
**Source**: https://4ort.xyz/entity/nodal-q22676929


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P43021)
3. Q20641742
4. [Dual roles of Cripto as a ligand and coreceptor in the nodal signaling pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43021)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43021)
6. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43021)
7. [Two modes by which Lefty proteins inhibit nodal signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43021)
8. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P43021&geneProductId=UniProtKB:P43021)
9. [Nodal is a novel TGF-beta-like gene expressed in the mouse node during gastrulation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P43021&geneProductId=UniProtKB:P43021)
10. [Nodal is a novel TGF-beta-like gene expressed in the mouse node during gastrulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43021)
11. [Nodal regulates trophoblast differentiation and placental development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43021)
12. [Genetic dissection of nodal function in patterning the mouse embryo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43021)
13. [Cerberus is a feedback inhibitor of Nodal asymmetric signaling in the chick embryo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43021)
14. [Cell fate decisions within the mouse organizer are governed by graded Nodal signals](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43021)
15. [NODAL in the uterus is necessary for proper placental development and maintenance of pregnancy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43021)
16. [Control of early anterior-posterior patterning in the mouse embryo by TGF-β signalling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43021)
17. [The tumor suppressor gene Smad4/Dpc4 is required for gastrulation and later for anterior development of the mouse embryo](http://www.ebi.ac.uk/QuickGO/annotations?protein=P43021&geneProductId=UniProtKB:P43021)
18. [Eosinophils and T lymphocytes possess distinct roles in bleomycin-induced lung injury and fibrosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43021)
19. [A primary requirement for nodal in the formation and maintenance of the primitive streak in the mouse](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43021)
20. [ALK7, a receptor for nodal, is dispensable for embryogenesis and left-right patterning in the mouse](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43021)
21. [Inhibition of Nodal suppresses angiogenesis and growth of human gliomas](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43021)
22. [Absence of Nodal signaling promotes precocious neural differentiation in the mouse embryo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43021)
23. [Nodal protein processing and fibroblast growth factor 4 synergize to maintain a trophoblast stem cell microenvironment](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43021)
24. [Heart defects in X-linked heterotaxy: evidence for a genetic interaction of Zic3 with the nodal signaling pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43021)
25. [X-linked situs abnormalities result from mutations in ZIC3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43021)
26. [Nodal activity in the node governs left-right asymmetry](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43021)
27. [The activity of the Nodal antagonist Cerl-2 in the mouse node is required for correct L/R body axis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43021)
28. [Nodal signaling induces the midline barrier by activating Nodal expression in the lateral plate](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43021)
29. [Left-right patterning of the mouse lateral plate requires nodal produced in the node](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43021)
30. [Distinct and cooperative roles of mammalian Vg1 homologs GDF1 and GDF3 during early embryonic development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43021)
31. [Nodal antagonists regulate formation of the anteroposterior axis of the mouse embryo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43021)
32. [Multiple roles for Nodal in the epiblast of the mouse embryo in the establishment of anterior-posterior patterning](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43021)
33. [Tgif1 and Tgif2 regulate Nodal signaling and are required for gastrulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43021)
34. [Correct patterning of the primitive streak requires the anterior visceral endoderm](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43021)
35. [Endogenous Nodal signaling regulates germ cell potency during mammalian testis development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43021)
36. [Nodal signalling in the epiblast patterns the early mouse embryo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43021)
37. [Foxh1 recruits Gsc to negatively regulate Mixl1 expression during early mouse development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43021)
38. [The tumor suppressor gene Smad4/Dpc4 is required for gastrulation and later for anterior development of the mouse embryo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43021)
39. ensembl Release 106