# NLR family, pyrin domain containing 3

> mammalian protein found in Mus musculus

**Wikidata**: [Q14905621](https://www.wikidata.org/wiki/Q14905621)  
**Source**: https://4ort.xyz/entity/nlr-family-pyrin-domain-containing-3-q14905621


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q8R4B8)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4B8)
5. [The receptor NLRP3 is a transcriptional regulator of TH2 differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4B8)
6. [Novel role of PKR in inflammasome activation and HMGB1 release](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4B8)
7. [GBP5 promotes NLRP3 inflammasome assembly and immunity in mammals](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4B8)
8. [Syk is involved in NLRP3 inflammasome-mediated caspase-1 activation through adaptor ASC phosphorylation and enhanced oligomerization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4B8)
9. [NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4B8)
10. [The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4B8)
11. [Hexokinase Is an Innate Immune Receptor for the Detection of Bacterial Peptidoglycan](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4B8)
12. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8R4B8&geneProductId=UniProtKB:Q8R4B8)
13. [NLRP1-dependent pyroptosis leads to acute lung injury and morbidity in mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4B8)
14. [Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4B8)
15. [Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4B8)
16. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4B8)
17. [NLRP3 mutation and cochlear autoinflammation cause syndromic and nonsyndromic hearing loss DFNA34 responsive to anakinra therapy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4B8)
18. ensembl Release 106