# NLR family, CARD domain containing 4

> mammalian protein found in Mus musculus

**Wikidata**: [Q21986189](https://www.wikidata.org/wiki/Q21986189)  
**Source**: https://4ort.xyz/entity/nlr-family-card-domain-containing-4-q21986189


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q3UP24)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UP24)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q3UP24&geneProductId=UniProtKB:Q3UP24)
6. [Phosphorylation of NLRC4 is critical for inflammasome activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UP24)
7. [Structural and biochemical basis for induced self-propagation of NLRC4.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UP24)
8. [Cryoelectron Tomography of the NAIP5/NLRC4 Inflammasome: Implications for NLR Activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UP24)
9. [Cryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UP24)
10. [Crystal structure of NLRC4 reveals its autoinhibition mechanism](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UP24)
11. [Cryoelectron Tomography of the NAIP5/NLRC4 Inflammasome: Implications for NLR Activation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q3UP24&geneProductId=UniProtKB:Q3UP24)
12. [Structural and biochemical basis for induced self-propagation of NLRC4.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q3UP24&geneProductId=UniProtKB:Q3UP24)
13. [Cryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q3UP24&geneProductId=UniProtKB:Q3UP24)
14. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UP24)
15. [Phosphorylation of NLRC4 is critical for inflammasome activation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q3UP24&geneProductId=UniProtKB:Q3UP24)
16. [Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q3UP24&geneProductId=UniProtKB:Q3UP24)
17. [Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UP24)
18. [Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UP24)
19. [Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q3UP24&geneProductId=UniProtKB:Q3UP24)
20. [NLRC4-driven production of IL-1β discriminates between pathogenic and commensal bacteria and promotes host intestinal defense](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q3UP24&geneProductId=UniProtKB:Q3UP24)
21. [Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q3UP24&geneProductId=UniProtKB:Q3UP24)
22. [Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q3UP24&geneProductId=UniProtKB:Q3UP24)
23. [Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UP24)
24. [Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UP24)
25. [NLRC4-driven production of IL-1β discriminates between pathogenic and commensal bacteria and promotes host intestinal defense](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3UP24)
26. ensembl Release 106