# Nitric oxide synthase 2

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28561743](https://www.wikidata.org/wiki/Q28561743)  
**Source**: https://4ort.xyz/entity/nitric-oxide-synthase-2-q28561743


## References

1. UniProt
2. Q20641742
3. [Regulation of Sertoli-germ cell adherens junction dynamics in the testis via the nitric oxide synthase (NOS)/cGMP/protein kinase G (PRKG)/beta-catenin (CATNB) signaling pathway: an in vitro and in vivo study](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518)
4. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518)
5. [Complete coding sequence of inducible nitric oxide synthase from human heart and skeletal muscle of patients with chronic heart failure](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518)
6. [Inducible nitric oxide synthase expression of tumor and stromal cells is associated with the progression of 7,12-dimethylbenz[a]anthracene-induced rat mammary tumors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518)
7. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518)
8. [Monomeric inducible nitric oxide synthase localizes to peroxisomes in hepatocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518)
9. [Inducible nitric oxide synthase plays a role in LPS-induced hyperglycemia and insulin resistance](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518)
10. [Heterologous down-regulation of angiotensin type 1 receptors by purinergic P2Y 2 receptor stimulation through S-nitrosylation of NF-κB](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518)
11. [Attenuation of cAMP accumulation in adult rat cardiac fibroblasts by IL-1beta and NO: role of cGMP-stimulated PDE2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518)
12. [iNOS regulation by calcium/calmodulin-dependent protein kinase II in vascular smooth muscle](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518)
13. [Heat shock regulates the respiration of cardiac H9c2 cells through upregulation of nitric oxide synthase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518)
14. [Anti-inflammatory activities and mechanisms of action of the petroleum ether fraction of Rosa multiflora Thunb. hips](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518)
15. [Nitric oxide synthase localization in the rat neutrophils: immunocytochemical, molecular, and biochemical studies](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518)
16. [Evidence for a functional nitric oxide synthase system in brown adipocyte nucleus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518)
17. [Peroxisomal localization of inducible nitric oxide synthase in hepatocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518)
18. [Subcellular distribution of nitric oxide synthase isoforms in the rat duodenum](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518)
19. [Relationship between iNOS expression and aortic cell proliferation and apoptosis in an elastase-induced model of aorta aneurysm and the effect of 1400 W administration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518)
20. [Association between the expression of inducible nitric oxide synthase by chondrocytes and its nitric oxide-generating activity in adjuvant arthritis in rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518)
21. [Endothelial dysfunction in the early- and late-stage type-2 diabetic Goto-Kakizaki rat aorta](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518)
22. [Cardiovascular responses and neurotransmitter changes during static muscle contraction following blockade of inducible nitric oxide synthase (iNOS) within the ventrolateral medulla](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518)
23. [Accelerated ubiquitination and proteasome degradation of a genetic variant of inducible nitric oxide synthase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518)
24. [Orthodontic force stimulates eNOS and iNOS in rat osteocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518)
25. [Regulation of inducible nitric oxide synthase activity/expression in rat hearts from ghrelin-treated rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518)
26. [Oxidative injury due to chronic nitric oxide synthase inhibition in rat: effect of regular exercise on the heart](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518)
27. [Influence of N-methyl-D-aspartate receptors on ouabain activation of nuclear factor-κB in the rat hippocampus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518)
28. [Effect of 17beta-estradiol on myocardial inducible NOS and endothelial NOS activities after ischemia-reperfusion in rat heart model](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518)
29. [Regulation of the urea cycle enzyme genes in nitric oxide synthesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518)
30. [TNF-alpha modulates iNOS expression in an experimental rat model of indomethacin-induced jejunoileitis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518)
31. [Angiotensin II differentially regulates interleukin-1-beta-inducible NO synthase (iNOS) and vascular cell adhesion molecule-1 (VCAM-1) expression: role of p38 MAPK](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518)
32. [Mangiferin decreases inflammation and oxidative damage in rat brain after stress](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518)
33. [Upregulation of the production of interferon-γ and the gene expression of the inducible nitric oxide synthase after excimer laser ablation in rat corneas](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518)
34. [iNOS enhances rat intestinal apoptosis after ischemia-reperfusion](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518)
35. [Retinoic acid inhibits expression of TNF-alpha and iNOS in activated rat microglia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518)
36. [Role of neuronal nitric oxide synthase and inducible nitric oxide synthase in intestinal injury in neonatal rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518)
37. [Antioxidative and anti-inflammatory effects of phenolic compounds from the roots of Ulmus macrocarpa](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518)
38. [Effects of lithium on lipopolysaccharide-induced inflammation in rat primary glia cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518)
39. [1,25-Dihydroxyvitamin D3 prevented allergic asthma in a rat model by suppressing the expression of inducible nitric oxide synthase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518)
40. [JANEX-1, a JAK3 inhibitor, protects pancreatic islets from cytokine toxicity through downregulation of NF-kappaB activation and the JAK/STAT pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518)
41. [Tetrandrine down-regulates ERK/NF-κB signaling and inhibits activation of mesangial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518)
42. [Reciprocal Regulation between Proinflammatory Cytokine-induced Inducible NO Synthase (iNOS) and Connexin43 in Bladder Smooth Muscle Cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518)
43. [Extracellular cysteine (Cys)/cystine (CySS) redox regulates metabotropic glutamate receptor 5 activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518)
44. [Biochemical and genetic alterations of oxidant/antioxidant status of the brain in rats treated with dexamethasone: protective roles of melatonin and acetyl-L-carnitine](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06518)
45. ensembl Release 106