# Nitric oxide synthase 1

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28556599](https://www.wikidata.org/wiki/Q28556599)  
**Source**: https://4ort.xyz/entity/nitric-oxide-synthase-1-q28556599


## References

1. UniProt
2. Q20641742
3. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29476)
4. [Nitrergic dendrites in the superficial layers of the rat superior colliculus: retinal afferents and alternatively spliced isoforms in normal and deafferented animals](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29476)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29476)
6. [Nitric oxide synthase localization in the rat neutrophils: immunocytochemical, molecular, and biochemical studies](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29476)
7. [A conserved aspartate (Asp-1393) regulates NADPH reduction of neuronal nitric-oxide synthase: implications for catalysis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29476)
8. [Role of Asp1393 in catalysis, flavin reduction, NADP(H) binding, FAD thermodynamics, and regulation of the nNOS flavoprotein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29476)
9. [Spectral characterization of brain and macrophage nitric oxide synthases. Cytochrome P-450-like hemeproteins that contain a flavin semiquinone radical](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29476)
10. [Syntrophin mutation associated with long QT syndrome through activation of the nNOS-SCN5A macromolecular complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29476)
11. [Dexras1: a G protein specifically coupled to neuronal nitric oxide synthase via CAPON](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29476)
12. [Neuronal nitric-oxide synthase localization mediated by a ternary complex with synapsin and CAPON.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29476)
13. [Cellulose membrane supported peptide arrays for deciphering protein-protein interaction sites: the case of PIN, a protein with multiple natural partners](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29476)
14. [Arginase modulates myocardial contractility by a nitric oxide synthase 1-dependent mechanism](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29476)
15. [Elevated expression of CAPON and neuronal nitric oxide synthase in the sciatic nerve of rats following constriction injury](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29476)
16. [Dynamin activates NO production in rat renal inner medullary collecting ducts via protein-protein interaction with NOS1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29476)
17. [Heat-shock protein 90 augments neuronal nitric oxide synthase activity by enhancing Ca2+/calmodulin binding](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29476)
18. [Rate, affinity and calcium dependence of nitric oxide synthase isoform binding to the primary physiological regulator calmodulin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29476)
19. [CAPON: A Protein Associated with Neuronal Nitric Oxide Synthase that Regulates Its Interactions with PSD95](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29476)
20. [A bridging interaction allows calmodulin to activate NO synthase through a bi-modal mechanism](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29476)
21. [Role of bound zinc in dimer stabilization but not enzyme activity of neuronal nitric-oxide synthase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29476)
22. [Diabetes induces sex-dependent changes in neuronal nitric oxide synthase dimerization and function in the rat gastric antrum](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29476)
23. [Angiotensin II-mediated posttranslational modification of nNOS in the PVN of rats with CHF: role for PIN](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29476)
24. [The plasmamembrane calmodulin-dependent calcium pump: a major regulator of nitric oxide synthase I](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29476)
25. [Binding of neuronal nitric-oxide synthase (nNOS) to carboxyl-terminal-binding protein (CtBP) changes the localization of CtBP from the nucleus to the cytosol: a novel function for targeting by the PDZ domain of nNOS](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29476)
26. [Nitric oxide synthase in retina and optic nerve head of rat with increased intraocular pressure and effect of timolol](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29476)
27. [Hypothyroid phenotype is contributed by mitochondrial complex I inactivation due to translocated neuronal nitric-oxide synthase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29476)
28. [Subcellular distribution of nitric oxide synthase isoforms in the rat duodenum](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29476)
29. [Synaptic localization of nitric oxide synthase and soluble guanylyl cyclase in the hippocampus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29476)
30. [Kainate-induced seizures alter protein composition and N-methyl-D-aspartate receptor function of rat forebrain postsynaptic densities](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29476)
31. [A neuronal isoform of nitric oxide synthase expressed in pancreatic beta-cells controls insulin secretion](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29476)
32. [Nitric oxide in skeletal muscle](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29476)
33. [Chronic intermittent hypoxia modulates nNOS mRNA and protein expression in the rat hypothalamus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29476)
34. [Hypoxia induces a functionally significant and translationally efficient neuronal NO synthase mRNA variant](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29476)
35. [Specific role of neuronal nitric-oxide synthase when tethered to the plasma membrane calcium pump in regulating the beta-adrenergic signal in the myocardium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29476)
36. [Neuronal nitric oxide synthase (bNOS) messenger RNA and protein expression in developing rat brainstem nuclei](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29476)
37. [Renal nitric oxide production in rat pregnancy: role of constitutive nitric oxide synthases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29476)
38. [Renal redox response to normal pregnancy in the rat](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29476)
39. [Y-27632 improves the erectile dysfunction with ageing in SD rats through adjusting the imbalance between nNo and the Rho-kinase pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29476)
40. [Neuronal nitric oxide inhibits intestinal smooth muscle growth](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29476)
41. [Inhibition of neuronal nitric oxide synthase causes attenuation of cerebrovascular dysfunction in experimental heatstroke](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29476)
42. [Plasticity of basal ganglia neurocircuitries following perinatal asphyxia: effect of nicotinamide](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29476)
43. [Nitric oxide synthase immunolocalization and expression in the rat hippocampus after sub-acute lead acetate exposure in rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29476)
44. [Effect of ligustrazine on cell proliferation in subventricular zone in rat brain with focal cerebral ischemia-reperfusion injury](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29476)
45. [The effect of regular exercise on penile nitric oxide synthase expression in rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29476)
46. [Perinatal food restriction impaired spatial learning and memory behavior and decreased the density of nitric oxide synthase neurons in the hippocampus of adult male rat offspring](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29476)
47. [In vitro and in vivo induction and activation of nNOS by LPS in oligodendrocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29476)
48. [Vitamin E reduces glomerulosclerosis, restores renal neuronal NOS, and suppresses oxidative stress in the 5/6 nephrectomized rat](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29476)
49. [1-Methyl-4-phenylpyridinium-induced apoptosis in cerebellar granule neurons is mediated by transferrin receptor iron-dependent depletion of tetrahydrobiopterin and neuronal nitric-oxide synthase-derived superoxide](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29476)
50. [Hippocampal neuronal nitric oxide synthase (nNOS) is regulated by nicotine and stress in female but not in male rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29476)