# NHL repeat containing E3 ubiquitin protein ligase 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21110884](https://www.wikidata.org/wiki/Q21110884)  
**Source**: https://4ort.xyz/entity/nhl-repeat-containing-e3-ubiquitin-protein-ligase-1-q21110884


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q6VVB1)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VVB1)
5. [Insights into Lafora disease: malin is an E3 ubiquitin ligase that ubiquitinates and promotes the degradation of laforin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VVB1)
6. [A role for AGL ubiquitination in the glycogen storage disorders of Lafora and Cori's disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VVB1)
7. [Early-onset Lafora body disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VVB1)
8. [Laforin is required for the functional activation of malin in endoplasmic reticulum stress resistance in neuronal cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VVB1)
9. [Lafora progressive myoclonus epilepsy: NHLRC1 mutations affect glycogen metabolism](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VVB1)
10. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6VVB1&geneProductId=UniProtKB:Q6VVB1)
11. [Malin decreases glycogen accumulation by promoting the degradation of protein targeting to glycogen (PTG)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VVB1)
12. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6VVB1)
13. [A role for AGL ubiquitination in the glycogen storage disorders of Lafora and Cori's disease](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6VVB1&geneProductId=UniProtKB:Q6VVB1)
14. [Insights into Lafora disease: malin is an E3 ubiquitin ligase that ubiquitinates and promotes the degradation of laforin](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6VVB1&geneProductId=UniProtKB:Q6VVB1)
15. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6VVB1&geneProductId=UniProtKB:Q6VVB1)
16. Ensembl Release 99