# Neurotrophic tyrosine kinase, receptor, type 2

> mammalian protein found in Mus musculus

**Wikidata**: [Q14901163](https://www.wikidata.org/wiki/Q14901163)  
**Source**: https://4ort.xyz/entity/neurotrophic-tyrosine-kinase-receptor-type-2


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P15209)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P15209)
5. [TrkB binds and tyrosine-phosphorylates Tiam1, leading to activation of Rac1 and induction of changes in cellular morphology](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P15209)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15209)
7. [The neurotrophic factors brain-derived neurotrophic factor and neurotrophin-3 are ligands for the trkB tyrosine kinase receptor](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P15209)
8. [Retrolinkin cooperates with endophilin A1 to mediate BDNF–TrkB early endocytic trafficking and signaling from early endosomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15209)
9. [TrkB binds and tyrosine-phosphorylates Tiam1, leading to activation of Rac1 and induction of changes in cellular morphology](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15209)
10. [Mechanism of TrkB-mediated hippocampal long-term potentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15209)
11. [Dissection of NT3 functions in vivo by gene replacement strategy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15209)
12. [BDNF-mediated neurotransmission relies upon a myosin VI motor complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15209)
13. [Protein-protein interaction panel using mouse full-length cDNAs](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15209)
14. [Huntingtin-associated protein 1 regulates postnatal neurogenesis and neurotrophin receptor sorting](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15209)
15. [Impairment of TrkB-PSD-95 Signaling in Angelman Syndrome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15209)
16. [Sortilin associates with Trk receptors to enhance anterograde transport and neurotrophin signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15209)
17. [Myelin suppresses axon regeneration by PIR-B/SHP-mediated inhibition of Trk activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15209)
18. [Neuronal Abelson helper integration site-1 (Ahi1) deficiency in mice alters TrkB signaling with a depressive phenotype.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15209)
19. [A TrkB/EphrinA interaction controls retinal axon branching and synaptogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15209)
20. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15209)
21. [The neurotrophic factors brain-derived neurotrophic factor and neurotrophin-3 are ligands for the trkB tyrosine kinase receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15209)
22. [Christianson syndrome protein NHE6 modulates TrkB endosomal signaling required for neuronal circuit development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15209)
23. [Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15209&geneProductId=UniProtKB:P15209)
24. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15209&geneProductId=UniProtKB:P15209)
25. [Disruption of Trkb-mediated signaling induces disassembly of postsynaptic receptor clusters at neuromuscular junctions](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15209&geneProductId=UniProtKB:P15209)
26. [Spatial and temporal organization of TrkB expression in the developing musculature of the mouse esophagus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15209)
27. [Presenilin 1 and presenilin 2 have differential effects on the stability and maturation of nicastrin in Mammalian brain](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15209&geneProductId=UniProtKB:P15209)
28. [Nitric oxide acts in a positive feedback loop with BDNF to regulate neural progenitor cell proliferation and differentiation in the mammalian brain](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15209&geneProductId=UniProtKB:P15209)
29. [Sortilin-related receptor SORCS3 is a postsynaptic modulator of synaptic depression and fear extinction](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15209&geneProductId=UniProtKB:P15209)
30. [Nitric oxide acts in a positive feedback loop with BDNF to regulate neural progenitor cell proliferation and differentiation in the mammalian brain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15209)
31. [Presenilin 1 and presenilin 2 have differential effects on the stability and maturation of nicastrin in Mammalian brain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15209)
32. [Sortilin-related receptor SORCS3 is a postsynaptic modulator of synaptic depression and fear extinction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15209)
33. [Impaired synaptic function in the microglial KARAP/DAP12-deficient mouse.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15209)
34. [Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15209)
35. [Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15209)
36. [Disruption of Trkb-mediated signaling induces disassembly of postsynaptic receptor clusters at neuromuscular junctions](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P15209)
37. [Valproic Acid Prevents NMDA-Induced Retinal Ganglion Cell Death via Stimulation of Neuronal TrkB Receptor Signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15209)
38. [TrkB regulates neocortex formation through the Shc/PLCgamma-mediated control of neuronal migration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15209)
39. [Targeted disruption of the trkB neurotrophin receptor gene results in nervous system lesions and neonatal death](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15209)
40. [p75 neurotrophin receptor is a clock gene that regulates oscillatory components of circadian and metabolic networks](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15209)
41. [Coronary vessel development requires activation of the TrkB neurotrophin receptor by the Wilms' tumor transcription factor Wt1.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15209)
42. [Pacinian corpuscle development involves multiple Trk signaling pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15209)
43. [TrkB regulates neocortex formation through the Shc/PLCgamma-mediated control of neuronal migration](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P15209)
44. [Essential role for TrkB receptors in hippocampus-mediated learning](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15209)
45. [Brain-derived neurotrophic factor signaling rewrites the glucocorticoid transcriptome via glucocorticoid receptor phosphorylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15209)
46. [Role of neurotrophin receptor TrkB in the maturation of rod photoreceptors and establishment of synaptic transmission to the inner retina](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15209)
47. [Truncated TrkB-T1 mediates neurotrophin-evoked calcium signalling in glia cells](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P15209)
48. [Suppression of anoikis and induction of metastasis by the neurotrophic receptor TrkB](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15209)
49. [Calsyntenins Function as Synaptogenic Adhesion Molecules in Concert with Neurexins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15209)
50. [TrkB and TrkC agonist antibodies improve function, electrophysiologic and pathologic features in Trembler J mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15209)