Neurotrophic receptor tyrosine kinase 3
type: Thing
description: mammalian protein found in Rattus norvegicus
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P361
  value: Leucine-rich repeat domain superfamily
additional property: PropertyValue
  property ID: P361
  value: Immunoglobulin-like fold
additional property: PropertyValue
  property ID: P361
  value: Protein kinase-like domain superfamily
additional property: PropertyValue
  property ID: P527
  value: tyrosine-protein kinase, active site
additional property: PropertyValue
  property ID: P527
  value: immunoglobulin I-set
additional property: PropertyValue
  property ID: P527
  value: leucine-rich repeat N-terminal domain
additional property: PropertyValue
  property ID: P637
  value: NP_001257584
additional property: PropertyValue
  property ID: P637
  value: NP_001257585
additional property: PropertyValue
  property ID: P637
  value: NP_062121
additional property: PropertyValue
  property ID: P680
  value: nucleotide binding
additional property: PropertyValue
  property ID: P680
  value: p53 binding
additional property: PropertyValue
  property ID: P680
  value: protein kinase activity
additional property: PropertyValue
  property ID: P681
  value: Golgi membrane
additional property: PropertyValue
  property ID: P681
  value: cytoplasm
additional property: PropertyValue
  property ID: P681
  value: plasma membrane
additional property: PropertyValue
  property ID: P682
  value: neuron migration
additional property: PropertyValue
  property ID: P682
  value: negative regulation of protein phosphorylation
additional property: PropertyValue
  property ID: P682
  value: protein phosphorylation
additional property: PropertyValue
  property ID: P702
  value: Ntrk3
additional property: PropertyValue
  property ID: P703
  value: brown rat
additional property: PropertyValue
  property ID: P705
  value: ENSRNOP00000025536
additional property: PropertyValue
  property ID: P705
  value: ENSRNOP00000044402
additional property: PropertyValue
  property ID: P705
  value: ENSRNOP00000046059
confidence:
  popularity graph score:
    score: 0.003
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 21
      unique citations norm: 0.008
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 21
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: Q03351
    source count: 1
    confidence: 0.2
  P361:
    value: Q24781235
    source count: 1
    confidence: 0.2
    value label: Leucine-rich repeat domain superfamily
  P361:
    value: Q24787648
    source count: 1
    confidence: 0.2
    value label: Immunoglobulin-like fold
  P361:
    value: Q24726164
    source count: 1
    confidence: 0.2
    value label: Protein kinase-like domain superfamily
  P361:
    value: Q41797304
    source count: 1
    confidence: 0.2
    value label: Immunoglobulin-like domain superfamily
  P361:
    value: Q24768166
    source count: 1
    confidence: 0.2
    value label: tyrosine-protein kinase, neurotrophic receptor, type 3
  P527:
    value: Q24738472
    source count: 1
    confidence: 0.2
    value label: tyrosine-protein kinase, active site
  P527:
    value: Q24772334
    source count: 1
    confidence: 0.2
    value label: immunoglobulin I-set
  P527:
    value: Q24780524
    source count: 1
    confidence: 0.2
    value label: leucine-rich repeat N-terminal domain
  P527:
    value: Q24782645
    source count: 1
    confidence: 0.2
    value label: cysteine-rich flanking region, C-terminal
  P527:
    value: Q24770541
    source count: 1
    confidence: 0.2
    value label: immunoglobulin domain
  P637:
    value: NP_001257584
    source count: 1
    confidence: 0.2
  P637:
    value: NP_001257585
    source count: 1
    confidence: 0.2
  P637:
    value: NP_062121
    source count: 1
    confidence: 0.2
  P637:
    value: XP_008757735
    source count: 1
    confidence: 0.2
  P637:
    value: XP_017444550
    source count: 1
    confidence: 0.2
  P680:
    value: Q14860365
    source count: 1
    confidence: 0.2
    value label: nucleotide binding
  P680:
    value: Q14817974
    source count: 1
    confidence: 0.2
    value label: p53 binding
  P680:
    value: Q14820641
    source count: 1
    confidence: 0.2
    value label: protein kinase activity
  P680:
    value: Q21095347
    source count: 1
    confidence: 0.2
    value label: transmembrane receptor protein serine/threonine kinase activity
  P680:
    value: Q14863338
    source count: 2
    confidence: 0.4
    value label: protein tyrosine kinase activity
  P681:
    value: Q14598778
    source count: 1
    confidence: 0.2
    value label: Golgi membrane

value: Q79899
source count: 1
confidence: 0.2
value label: cytoplasm

value: Q29548
source count: 2
confidence: 0.4
value label: plasma membrane

value: Q14859540
source count: 2
confidence: 0.4
value label: integral component of plasma membrane

value: Q14349455
source count: 3
confidence: 0.6
value label: membrane

value: Q14330959
source count: 1
confidence: 0.2
value label: neuron migration

value: Q14860865
source count: 1
confidence: 0.2
value label: negative regulation of protein phosphorylation

value: Q7251493
source count: 1
confidence: 0.2
value label: protein phosphorylation

value: Q14863362
source count: 3
confidence: 0.6
value label: transmembrane receptor protein tyrosine kinase signaling pathway

value: Q14904951
source count: 1
confidence: 0.2
value label: transmembrane receptor protein serine/threonine kinase signaling pathway

value: Q24397346
source count: 1
confidence: 0.2
value label: Ntrk3

value: Q184224
source count: 1
confidence: 0.2
value label: brown rat

value: ENSRNOP00000025536
source count: 1
confidence: 0.2

value: ENSRNOP00000044402
source count: 1
confidence: 0.2

value: ENSRNOP00000046059
source count: 1
confidence: 0.2

value: ENSRNOP00000049463
source count: 1
confidence: 0.2

value: ENSRNOP00000096233
source count: 1
confidence: 0.2

source: GOA
stated in qid: Q28018111
retrieved: 2019-02-14

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2019-02-14

source: A TrkB/EphrinA interaction controls retinal axon branching and synaptogenesis
stated in qid: Q24318622
retrieved: 2019-02-14

source: JIP3 Mediates TrkB Axonal Anterograde Transport and Enhances BDNF Signaling by Directly Bridging TrkB with Kinesin-1
stated in qid: Q39503485
retrieved: 2019-02-14

source: TRPC5 channel is the mediator of neurotrophin-3 in regulating dendritic growth via CaMKIIα in rat hippocampal neurons
stated in qid: Q28565811
retrieved: 2019-02-14

source: Cdk5 is involved in BDNF-stimulated dendritic growth in hippocampal neurons
stated in qid: Q33277107
retrieved: 2019-02-14

source: Neurotrophin-3 administration alters neurotrophin, neurotrophin receptor and nestin mRNA expression in rat dorsal root ganglia following axotomy
stated in qid: Q28573799
retrieved: 2019-02-14

source: Presence and localization of neurotrophins and neurotrophin receptors in rat lacrimal gland
stated in qid: Q28566464
retrieved: 2019-02-14

source: Postsynaptic TrkC and presynaptic PTPσ function as a bidirectional excitatory synaptic organizing complex.
stated in qid: Q42684082
retrieved: 2019-02-14

source: TrkC overexpression enhances survival and migration of neural stem cell transplants in the rat spinal cord
stated in qid: Q28572313
retrieved: 2019-02-14

source: Alternative forms of rat TrkC with different functional capabilities
stated in qid: Q28583560
retrieved: 2019-02-14

source: Alterations in neurotrophin and neurotrophin receptor gene expression patterns in the rat central nervous system following perinatal Borna disease virus infection
stated in qid: Q28576533
retrieved: 2019-02-14

source: Ethanol-induced alterations of neurotrophin receptor expression on Purkinje cells in the neonatal rat cerebellum
stated in qid: Q28579479
retrieved: 2019-02-14

source: Expressing TrkC from the TrkA locus causes a subset of dorsal root ganglia neurons to switch fate
stated in qid: Q28569230
retrieved: 2019-02-14

source: Early postnatal corticosterone administration regulates neurotrophins and their receptors in septum and hippocampus of the rat
stated in qid: Q28575690
retrieved: 2019-02-14

source: Retinoic acid and neurotrophins collaborate to regulate neurogenesis in adult-derived neural stem cell cultures
stated in qid: Q28566301
retrieved: 2019-02-14

source: Differential expression of trkB.T1 and trkB.T2, truncated trkC, and p75(NGFR) in the cochlea prior to hearing function
stated in qid: Q28580769
retrieved: 2019-02-14

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2022-05-25

source: Q20641742
stated in qid: Q20641742
retrieved: 2022-03-20

source: ensembl Release 106
stated in qid: Q111699881

wikidata id: Q28556100
domain: protein
level: standard
html url: https://4ort.xyz/entity/neurotrophic-receptor-tyrosine-kinase-3-q28556100
markdown url: https://4ort.xyz/entity/neurotrophic-receptor-tyrosine-kinase-3-q28556100.md
facts url summary: https://4ort.xyz/entity/neurotrophic-receptor-tyrosine-kinase-3-q28556100/facts.json
facts url standard: https://4ort.xyz/entity/neurotrophic-receptor-tyrosine-kinase-3-q28556100/facts.json
facts url full: https://4ort.xyz/entity/neurotrophic-receptor-tyrosine-kinase-3-q28556100/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-04T04:23:38.736451Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T15:27:14.058956+00:00Z