# Neurotrophic receptor tyrosine kinase 2

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28559477](https://www.wikidata.org/wiki/Q28559477)  
**Source**: https://4ort.xyz/entity/neurotrophic-receptor-tyrosine-kinase-2-q28559477


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q63604)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63604)
5. [Rapid activation of the extracellular signal-regulated kinase 1/2 (ERK1/2) signaling pathway by electroconvulsive shock in the rat prefrontal cortex is not associated with TrkB neurotrophin receptor activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63604)
6. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63604)
7. [Brain-derived neurotrophic factor regulation of N-methyl-D-aspartate receptor-mediated synaptic currents in suprachiasmatic nucleus neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63604)
8. [Trkb receptors modulation of glutamate release is limited to a subset of nerve terminals in the adult rat hippocampus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63604)
9. [Activation loop tyrosines contribute varying roles to TrkB autophosphorylation and signal transduction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63604)
10. [JIP3 Mediates TrkB Axonal Anterograde Transport and Enhances BDNF Signaling by Directly Bridging TrkB with Kinesin-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63604)
11. [TrkB-mediated activation of geranylgeranyltransferase I promotes dendritic morphogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63604)
12. [Myelin suppresses axon regeneration by PIR-B/SHP-mediated inhibition of Trk activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63604)
13. [Cdk5 is involved in BDNF-stimulated dendritic growth in hippocampal neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63604)
14. [Glucocorticoid receptor interaction with TrkB promotes BDNF-triggered PLC-gamma signaling for glutamate release via a glutamate transporter](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63604)
15. [TrkB binds and tyrosine-phosphorylates Tiam1, leading to activation of Rac1 and induction of changes in cellular morphology](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63604)
16. [Naturally occurring truncated trkB receptors have dominant inhibitory effects on brain-derived neurotrophic factor signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63604)
17. [The neurotrophic factors brain-derived neurotrophic factor and neurotrophin-3 are ligands for the trkB tyrosine kinase receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63604)
18. [Temporal and spatial differences in expression of TrkB isoforms in rat retina during constant light exposure](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63604)
19. [Patterns of expression of brain-derived neurotrophic factor and tyrosine kinase B mRNAs and distribution and ultrastructural localization of their proteins in the visual pathway of the adult rat](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63604)
20. [The dynamic distribution of TrkB receptors before, during, and after synapse formation between cortical neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63604)
21. [Kainate-induced seizures alter protein composition and N-methyl-D-aspartate receptor function of rat forebrain postsynaptic densities](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63604)
22. [Myosin5a mediates BDNF-induced postendocytic recycling of full-length TrkB and its translocation into dendritic spines](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63604)
23. [Co-localization of caldesmon and calponin with cortical afferents, metabotropic glutamate and neurotrophic receptors in the lateral and central nuclei of the amygdala](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63604)
24. [Up-regulation of dorsal root ganglia BDNF and trkB receptor in inflammatory pain: an in vivo and in vitro study](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63604)
25. [The effect of age and tongue exercise on BDNF and TrkB in the hypoglossal nucleus of rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63604)
26. [7,8-dihydroxyflavone, a TrkB receptor agonist, blocks long-term spatial memory impairment caused by immobilization stress in rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63604)
27. [Impact of sound exposure and aging on brain-derived neurotrophic factor and tyrosine kinase B receptors levels in dorsal cochlear nucleus 80 days following sound exposure](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63604)
28. [The TrkB-Shc site signals neuronal survival and local axon growth via MEK and P13-kinase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63604)
29. [Sequential activation of p75 and TrkB is involved in dendritic development of subventricular zone-derived neuronal progenitors in vitro](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63604)
30. [Brain-derived neurotrophic factor signaling rewrites the glucocorticoid transcriptome via glucocorticoid receptor phosphorylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63604)
31. ensembl Release 106