# Neurotrophic receptor tyrosine kinase 1

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28558488](https://www.wikidata.org/wiki/Q28558488)  
**Source**: https://4ort.xyz/entity/neurotrophic-receptor-tyrosine-kinase-1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P35739)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35739)
5. [The protein phosphatase 2A regulatory subunits B'beta and B'delta mediate sustained TrkA neurotrophin receptor autophosphorylation and neuronal differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35739)
6. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35739)
7. [A TrkB/EphrinA interaction controls retinal axon branching and synaptogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35739)
8. [Reciprocal modulation of TrkA and p75NTR affinity states is mediated by direct receptor interactions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35739)
9. [GGA3 mediates TrkA endocytic recycling to promote sustained Akt phosphorylation and cell survival](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35739)
10. [Rap1-PDZ-GEF1 interacts with a neurotrophin receptor at late endosomes, leading to sustained activation of Rap1 and ERK and neurite outgrowth](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35739)
11. [Interaction of Mint2 with TrkA is involved in regulation of nerve growth factor-induced neurite outgrowth](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35739)
12. [Endophilin B1 as a novel regulator of nerve growth factor/ TrkA trafficking and neurite outgrowth.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35739)
13. [Activity-dependent interaction of the intracellular domain of rat trkA with intermediate filament proteins, the beta-6 proteasomal subunit, Ras-GRF1, and the p162 subunit of eIF3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35739)
14. [Direct binding of the signaling adapter protein Grb2 to the activation loop tyrosines on the nerve growth factor receptor tyrosine kinase, TrkA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35739)
15. [Tyrosine kinase nerve growth factor receptor switches from prosurvival to proapoptotic activity via Abeta-mediated phosphorylation.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35739)
16. [Association of the Abl tyrosine kinase with the Trk nerve growth factor receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35739)
17. [Effect of amyloid peptides on the increase in TrkA receptor expression induced by nicotine in vitro and in vivo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35739)
18. [Nerve growth factor applied onto the olfactory epithelium alleviates degenerative changes of the olfactory receptor neurons following axotomy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35739)
19. [Ultrastructural localization of the neurotrophin receptor (TrkA) in cultured rat pheochromocytoma PC12 Cells: three-dimensional image analysis by high voltage electron microscopy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35739)
20. [TrkA pathway(s) is involved in regulation of TRPM7 expression in hippocampal neurons subjected to ischemic-reperfusion and oxygen-glucose deprivation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35739)
21. [Guiding adult Mammalian sensory axons during regeneration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35739)
22. [Age-related regional differences in cardiac nerve growth factor expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35739)
23. [Age-dependent alterations in nerve growth factor (NGF)-related proteins, sortilin, and learning and memory in rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35739)
24. [Targeted silencing of TrkA expression in rat forebrain neurons via the p75 receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35739)
25. [Electroacupuncture counteracts the development of thermal hyperalgesia and the alteration of nerve growth factor and sensory neuromodulators induced by streptozotocin in adult rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35739)
26. [Neurotrophin receptors TrkA and TrkC cause neuronal death whereas TrkB does not](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35739)
27. [Neurotrophins and tonsillar hypertrophy in children with obstructive sleep apnea](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35739)
28. [Sequential expression of Trks A, B, and C in the regenerating olfactory neuroepithelium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35739)
29. [A high soy diet enhances neurotropin receptor and Bcl-XL gene expression in the brains of ovariectomized female rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35739)
30. [Nicotine increases the expression of neurotrophin receptor tyrosine kinase receptor A in basal forebrain cholinergic neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35739)
31. [Neurosteroid dehydroepiandrosterone interacts with nerve growth factor (NGF) receptors, preventing neuronal apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35739)
32. [Inhibition of p75(NTR) in glia potentiates TrkA-mediated survival of injured retinal ganglion cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35739)
33. [Differential regulation of the expression of neurotrophin receptors in rat extraocular motoneurons after lesion](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35739)
34. [Local Administration of a Synthetic Cell-Penetrating Peptide Antagonizing TrkA Function Suppresses Inflammatory Pain in Rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35739)
35. [Reduced NGF level and TrkA protein and TrkA gene expression in the optic nerve of rats with experimentally induced glaucoma](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35739)
36. [Immunohistochemical evaluation of the protein expression of nerve growth factor and its TrkA receptor in rat limbic regions following electroshock seizures](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35739)
37. [Neonatal tissue damage facilitates nociceptive synaptic input to the developing superficial dorsal horn via NGF-dependent mechanisms](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35739)
38. [Initiation of testicular tubulogenesis is controlled by neurotrophic tyrosine receptor kinases in a three-dimensional Sertoli cell aggregation assay](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35739)
39. [Chronic and Acute Models of Retinal Neurodegeneration TrkA Activity Are Neuroprotective whereas p75NTR Activity Is Neurotoxic through a Paracrine Mechanism](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35739)
40. ensembl Release 104