# Neuropilin 1

> mammalian protein found in Mus musculus

**Wikidata**: [Q21985312](https://www.wikidata.org/wiki/Q21985312)  
**Source**: https://4ort.xyz/entity/neuropilin-1-q21985312


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P97333)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97333)
5. [Neuropilin 1 (NRP1) hypomorphism combined with defective VEGF-A binding reveals novel roles for NRP1 in developmental and pathological angiogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97333)
6. [Differential expression of VEGF isoforms and VEGF(164)-specific receptor neuropilin-1 in the mouse uterus suggests a role for VEGF(164) in vascular permeability and angiogenesis during implantation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97333)
7. [CMT2D neuropathy is linked to the neomorphic binding activity of glycyl-tRNA synthetase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97333)
8. [Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97333)
9. [The neural adhesion molecule TAG-1 modulates responses of sensory axons to diffusible guidance signals](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97333)
10. [Semaphorin 4B interacts with the post-synaptic density protein PSD-95/SAP90 and is recruited to synapses through a C-terminal PDZ-binding motif](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97333)
11. [PlexinD1 and semaphorin signaling are required in endothelial cells for cardiovascular development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97333)
12. [Neuropilin-1/GIPC1 signaling regulates alpha5beta1 integrin traffic and function in endothelial cells.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97333)
13. [FAK-MAPK-dependent adhesion disassembly downstream of L1 contributes to semaphorin3A-induced collapse](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97333)
14. [Osteoprotection by semaphorin 3A](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97333)
15. [Neuropilins lock secreted semaphorins onto plexins in a ternary signaling complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97333)
16. [Imatinib inhibits VEGF-independent angiogenesis by targeting neuropilin 1-dependent ABL1 activation in endothelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97333)
17. [PlexinD1 and semaphorin signaling are required in endothelial cells for cardiovascular development](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97333&geneProductId=UniProtKB:P97333)
18. [Identification and characterization of a novel mouse plexin, plexin-A4](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97333&geneProductId=UniProtKB:P97333)
19. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97333&geneProductId=UniProtKB:P97333)
20. [VEGF signaling through neuropilin 1 guides commissural axon crossing at the optic chiasm](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97333)
21. [Identification and characterization of a novel mouse plexin, plexin-A4](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97333)
22. [Autism spectrum disorder susceptibility gene TAOK2 affects basal dendrite formation in the neocortex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97333)
23. [The neuropilin 1 cytoplasmic domain is required for VEGF-A-dependent arteriogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97333)
24. [Plexin-a4 mediates axon-repulsive activities of both secreted and transmembrane semaphorins and plays roles in nerve fiber guidance](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97333)
25. [Arx homeobox gene is essential for development of mouse olfactory system](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97333&geneProductId=UniProtKB:P97333)
26. [VEGF signaling through neuropilin 1 guides commissural axon crossing at the optic chiasm](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97333&geneProductId=UniProtKB:P97333)
27. [VEGF signalling controls GnRH neuron survival via NRP1 independently of KDR and blood vessels](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97333&geneProductId=UniProtKB:P97333)
28. [Arx homeobox gene is essential for development of mouse olfactory system](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97333)
29. [VEGF signalling controls GnRH neuron survival via NRP1 independently of KDR and blood vessels](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97333)
30. [Regulation of dendritic branching and spine maturation by semaphorin3A-Fyn signaling.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97333)
31. [Neuropilin 1 and 2 control cranial gangliogenesis and axon guidance through neural crest cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97333)
32. [CCT chaperonin complex is required for efficient delivery of anthrax toxin into the cytosol of host cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97333)
33. [NRP1 acts cell autonomously in endothelium to promote tip cell function during sprouting angiogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97333)
34. [Plexin A3 and plexin A4 convey semaphorin signals during facial nerve development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97333)
35. [NRP1 and NRP2 cooperate to regulate gangliogenesis, axon guidance and target innervation in the sympathetic nervous system](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97333)
36. [Neuropilin-1 conveys semaphorin and VEGF signaling during neural and cardiovascular development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97333)
37. [Neuropilin-1 is required for endothelial tip cell guidance in the developing central nervous system](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97333)
38. [Selective requirements for NRP1 ligands during neurovascular patterning](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97333)
39. [The cytoplasmic domain of neuropilin 1 is dispensable for angiogenesis, but promotes the spatial separation of retinal arteries and veins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97333)
40. [Neuropilin-mediated neural crest cell guidance is essential to organise sensory neurons into segmented dorsal root ganglia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97333)
41. [Neuropilin 1 signaling guides neural crest cells to coordinate pathway choice with cell specification](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97333)
42. [Defective gonadotropin-releasing hormone neuron migration in mice lacking SEMA3A signalling through NRP1 and NRP2: implications for the aetiology of hypogonadotropic hypogonadism](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97333)
43. [Semaphorin signaling facilitates cleft formation in the developing salivary gland](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97333)
44. [Coordination of trigeminal axon navigation and patterning with tooth organ formation: epithelial-mesenchymal interactions, and epithelial Wnt4 and Tgfbeta1 regulate semaphorin 3a expression in the dental mesenchyme](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97333)
45. [Semaphorins III and IV repel hippocampal axons via two distinct receptors](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97333&geneProductId=UniProtKB:P97333)
46. [Neural crest-derived SEMA3C activates endothelial NRP1 for cardiac outflow tract septation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97333)
47. [NRP1 Regulates CDC42 Activation to Promote Filopodia Formation in Endothelial Tip Cells.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97333)
48. [Semaphorins III and IV repel hippocampal axons via two distinct receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97333)
49. ensembl Release 106