Neuroligin 1
type: Thing
description: mammalian protein found in Mus musculus
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P279
  value: protein
additional property: PropertyValue
  property ID: P361
  value: Neuroligin-1
additional property: PropertyValue
  property ID: P361
  value: Alpha/Beta hydrolase fold
additional property: PropertyValue
  property ID: P361
  value: Carboxylesterase type B
additional property: PropertyValue
  property ID: P527
  value: carboxylesterase, type B
additional property: PropertyValue
  property ID: P527
  value: carboxylesterase type B, conserved site
additional property: PropertyValue
  property ID: P637
  value: NP_001156859
additional property: PropertyValue
  property ID: P637
  value: NP_619607
additional property: PropertyValue
  property ID: P637
  value: XP_006535478
additional property: PropertyValue
  property ID: P638
  value: 3B3Q
additional property: PropertyValue
  property ID: P680
  value: PDZ domain binding
additional property: PropertyValue
  property ID: P680
  value: scaffold protein binding
additional property: PropertyValue
  property ID: P680
  value: carboxylic ester hydrolase activity
additional property: PropertyValue
  property ID: P681
  value: integral component of membrane
additional property: PropertyValue
  property ID: P681
  value: postsynaptic membrane
additional property: PropertyValue
  property ID: P681
  value: membrane
additional property: PropertyValue
  property ID: P682
  value: regulation of neuron differentiation
additional property: PropertyValue
  property ID: P682
  value: receptor localization to synapse
additional property: PropertyValue
  property ID: P682
  value: heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
additional property: PropertyValue
  property ID: P702
  value: Nlgn1
additional property: PropertyValue
  property ID: P703
  value: house mouse
additional property: PropertyValue
  property ID: P705
  value: ENSMUSP00000074565
additional property: PropertyValue
  property ID: P705
  value: ENSMUSP00000142200
additional property: PropertyValue
  property ID: P705
  value: ENSMUSP00000103944
confidence:
  popularity graph score:
    score: 0.006
    score pct: 1
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 42
      unique citations norm: 0.017
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 42
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P279:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: Q99K10
    source count: 1
    confidence: 0.2
  P361:
    value: Q24787258
    source count: 1
    confidence: 0.2
    value label: Neuroligin-1
  P361:
    value: Q24744945
    source count: 1
    confidence: 0.2
    value label: Alpha/Beta hydrolase fold
  P361:
    value: Q5038076
    source count: 1
    confidence: 0.2
    value label: Carboxylesterase type B
  P361:
    value: Q95351183
    source count: 1
    confidence: 0.2
    value label: Carboxylesterase type B, conserved site, protein family
  P527:
    value: Q24776460
    source count: 1
    confidence: 0.2
    value label: carboxylesterase, type B
  P527:
    value: Q24721656
    source count: 1
    confidence: 0.2
    value label: carboxylesterase type B, conserved site
  P637:
    value: NP_001156859
    source count: 1
    confidence: 0.2
  P637:
    value: NP_619607
    source count: 1
    confidence: 0.2
  P637:
    value: XP_006535478
    source count: 1
    confidence: 0.2
  P637:
    value: XP_006535479
    source count: 1
    confidence: 0.2
  P637:
    value: XP_006535481
    source count: 1
    confidence: 0.2
  P638:
    value: 3B3Q
    source count: 1
    confidence: 0.2
  P680:
    value: Q14860298
    source count: 2
    confidence: 0.4
    value label: PDZ domain binding
  P680:
    value: Q14864209
    source count: 2
    confidence: 0.4
    value label: scaffold protein binding
  P680:
    value: Q21096272
    source count: 1
    confidence: 0.2
    value label: carboxylic ester hydrolase activity
  P680:
    value: Q14861864
    source count: 2
    confidence: 0.4
    value label: protein dimerization activity
  P680:
    value: Q14901668
    source count: 1
    confidence: 0.2
    value label: cell adhesion molecule binding
  P681:
    value: Q14327652
    source count: 1
    confidence: 0.2
    value label: integral component of membrane
  P681:
    value: Q14864257
    source count: 1
    confidence: 0.2
    value label: postsynaptic membrane
  P681:
    value: Q14349455
    source count: 2
    confidence: 0.4
    value label: membrane

value: Q5419646
source count: 3
confidence: 0.6
value label: excitatory synapse

value: Q189073
source count: 1
confidence: 0.2
value label: cell junction

value: Q14873933
source count: 1
confidence: 0.2
value label: regulation of neuron differentiation

value: Q14331109
source count: 1
confidence: 0.2
value label: receptor localization to synapse

value: Q14865252
source count: 1
confidence: 0.2
value label: heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules

value: Q1185869
source count: 1
confidence: 0.2
value label: inhibitory postsynaptic potential

value: Q21116174
source count: 1
confidence: 0.2
value label: synaptic vesicle targeting

value: Q18295808
source count: 1
confidence: 0.2
value label: Nlgn1

value: Q83310
source count: 1
confidence: 0.2
value label: house mouse

value: ENSMUSP00000074565
source count: 1
confidence: 0.2

value: ENSMUSP00000142200
source count: 1
confidence: 0.2

value: ENSMUSP00000103944
source count: 1
confidence: 0.2

value: ENSMUSP00000142086
source count: 1
confidence: 0.2

source: GOA
stated in qid: Q28018111
retrieved: 2019-02-14

source: GOA
stated in qid: Q28018111
retrieved: 2017-02-28

source: Neurexin mediates the assembly of presynaptic terminals
stated in qid: Q28585766
retrieved: 2017-02-28

source: Activity-independent and subunit-specific recruitment of functional AMPA receptors at neurexin/neuroligin contacts
stated in qid: Q28508281
retrieved: 2017-02-28

source: Neuroligin expressed in nonneuronal cells triggers presynaptic development in contacting axons
stated in qid: Q22254603
retrieved: 2017-02-28

source: Synapse formation regulated by protein tyrosine phosphatase receptor T through interaction with cell adhesion molecules and Fyn
stated in qid: Q24323158
retrieved: 2019-02-14

source: Neurexin-Neuroligin Synaptic Complex Regulates Schizophrenia-Related DISC1/Kal-7/Rac1 “Signalosome”
stated in qid: Q40036187
retrieved: 2019-02-14

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2019-02-14

source: Activity-independent and subunit-specific recruitment of functional AMPA receptors at neurexin/neuroligin contacts
stated in qid: Q28508281
retrieved: 2019-02-14

source: Neurexin mediates the assembly of presynaptic terminals
stated in qid: Q28585766
retrieved: 2019-02-14

source: Neuroligin expressed in nonneuronal cells triggers presynaptic development in contacting axons
stated in qid: Q22254603
retrieved: 2019-02-14

source: Activity-dependent validation of excitatory versus inhibitory synapses by neuroligin-1 versus neuroligin-2
stated in qid: Q26269865
retrieved: 2019-02-14

source: Astn2, a novel member of the astrotactin gene family, regulates the trafficking of ASTN1 during glial-guided neuronal migration
stated in qid: Q28115873
retrieved: 2019-02-14

source: SynCAM, a synaptic adhesion molecule that drives synapse assembly
stated in qid: Q28219424
retrieved: 2017-02-28

source: Control of excitatory and inhibitory synapse formation by neuroligins
stated in qid: Q28568459
retrieved: 2017-02-28

source: mSYD1A, a mammalian synapse-defective-1 protein, regulates synaptogenic signaling and vesicle docking
stated in qid: Q24296506
retrieved: 2017-02-28

source: mSYD1A, a mammalian synapse-defective-1 protein, regulates synaptogenic signaling and vesicle docking
stated in qid: Q24296506
retrieved: 2019-02-14

source: A truncating mutation in Alzheimer's disease inactivates neuroligin-1 synaptic function
stated in qid: Q40036161
retrieved: 2019-02-14

source: Control of excitatory and inhibitory synapse formation by neuroligins
stated in qid: Q28568459
retrieved: 2019-02-14

source: SynCAM, a synaptic adhesion molecule that drives synapse assembly
stated in qid: Q28219424
retrieved: 2019-02-14

source: Neurexins induce differentiation of GABA and glutamate postsynaptic specializations via neuroligins
stated in qid: Q24336796
retrieved: 2019-02-14

source: Neuroligins/LRRTMs prevent activity- and Ca2+/calmodulin-dependent synapse elimination in cultured neurons
stated in qid: Q26269880
retrieved: 2019-02-14

source: Neuroligins determine synapse maturation and function
stated in qid: Q28505855
retrieved: 2017-02-28

source: Neuroligin-1-dependent competition regulates cortical synaptogenesis and synapse number
stated in qid: Q24303536
retrieved: 2019-02-14

source: Neuroligins determine synapse maturation and function
stated in qid: Q28505855
retrieved: 2019-02-14

source: Neurexins induce differentiation of GABA and glutamate postsynaptic specializations via neuroligins
stated in qid: Q24336796
retrieved: 2017-02-28

source: Neuroligin-1 links neuronal activity to sleep-wake regulation
stated in qid: Q28507569
retrieved: 2019-02-14

source: Developmental expression and subcellular distribution of synaptotagmin 11 in rat hippocampus
stated in qid: Q28512890
retrieved: 2019-02-14

source: Calsyntenins Function as Synaptogenic Adhesion Molecules in Concert with Neurexins
stated in qid: Q24338932
retrieved: 2019-02-14

source: Differential interactions of cerebellin precursor protein (Cbln) subtypes and neurexin variants for synapse formation of cortical neurons
stated in qid: Q28504807
retrieved: 2019-02-14

wikidata id: Q21987307
domain: protein
level: standard
html url: https://4ort.xyz/entity/neuroligin-1
markdown url: https://4ort.xyz/entity/neuroligin-1.md
facts url summary: https://4ort.xyz/entity/neuroligin-1/facts.json
facts url standard: https://4ort.xyz/entity/neuroligin-1/facts.json
facts url full: https://4ort.xyz/entity/neuroligin-1/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-24T12:29:39.405817Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T13:58:59.184953+00:00Z