# Neurofibromin 2

> mammalian protein found in Mus musculus

**Wikidata**: [Q14889820](https://www.wikidata.org/wiki/Q14889820)  
**Source**: https://4ort.xyz/entity/neurofibromin-2-q14889820


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P46662)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662)
5. [Merlin inhibits growth hormone-regulated Raf-ERKs pathways by binding to Grb2 protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662)
6. [NF2deficiency promotes tumorigenesis and metastasis by destabilizing adherens junctions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662)
7. [Merlin, the Product of the Nf2 Tumor Suppressor Gene, Is an Inhibitor of the p21-Activated Kinase, Pak1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662)
8. [Merlin/NF2 loss-driven tumorigenesis linked to CRL4(DCAF1)-mediated inhibition of the hippo pathway kinases Lats1 and 2 in the nucleus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662)
9. [Widespread but cell type-specific expression of the mouse neurofibromatosis type 2 gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662)
10. [JCV T-antigen interacts with the neurofibromatosis type 2 gene product in a transgenic mouse model of malignant peripheral nerve sheath tumors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662)
11. [Nf2–Yap signaling controls the expansion of DRG progenitors and glia during DRG development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662)
12. [Localization and functional domains of the neurofibromatosis type II tumor suppressor, merlin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662)
13. [Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662)
14. [Magicin, a novel cytoskeletal protein associates with the NF2 tumor suppressor merlin and Grb2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662)
15. [A growing family of Notch ligands](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662)
16. [The Nf2 tumor suppressor gene product is essential for extraembryonic development immediately prior to gastrulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662)
17. [Conditional biallelic Nf2 mutation in the mouse promotes manifestations of human neurofibromatosis type 2.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662)
18. [The Tumor Suppressor Merlin Is Required for Cell Cycle Exit, Terminal Differentiation, and Cell Polarity in the Developing Murine Lens](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662)
19. [Mice heterozygous for a mutation at the Nf2 tumor suppressor locus develop a range of highly metastatic tumors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662)
20. ensembl Release 106