# Nephronophthisis 3 (adolescent)

> mammalian protein found in Mus musculus

**Wikidata**: [Q21988814](https://www.wikidata.org/wiki/Q21988814)  
**Source**: https://4ort.xyz/entity/nephronophthisis-3-adolescent-


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q7TNH6)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TNH6)
5. [Inv acts as a molecular anchor for Nphp3 and Nek8 in the proximal segment of primary cilia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TNH6)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7TNH6&geneProductId=UniProtKB:Q7TNH6)
7. [Targeting of Nphp3 to the primary cilia is controlled by an N‐terminal myristoylation site and coiled‐coil domains](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7TNH6&geneProductId=UniProtKB:Q7TNH6)
8. [Loss of nephrocystin-3 function can cause embryonic lethality, Meckel-Gruber-like syndrome, situs inversus, and renal-hepatic-pancreatic dysplasia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TNH6)
9. [Abnormal lipid and fatty acid compositions of kidneys from mice with polycystic kidney disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TNH6)
10. [Altered extracellular matrix component gene expression in murine polycystic kidney](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TNH6)
11. [3D spheroid defects in NPHP knockdown cells are rescued by the somatostatin receptor agonist octreotide](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TNH6)
12. [Renal cyclooxygenase products are higher and lipoxygenase products are lower in early disease in the pcy mouse model of adolescent nephronophthisis](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7TNH6&geneProductId=UniProtKB:Q7TNH6)
13. [Loss of nephrocystin-3 function can cause embryonic lethality, Meckel-Gruber-like syndrome, situs inversus, and renal-hepatic-pancreatic dysplasia](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7TNH6&geneProductId=UniProtKB:Q7TNH6)
14. [Mutations in a novel gene, NPHP3, cause adolescent nephronophthisis, tapeto-retinal degeneration and hepatic fibrosis](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7TNH6&geneProductId=UniProtKB:Q7TNH6)
15. [Renal cyclooxygenase products are higher and lipoxygenase products are lower in early disease in the pcy mouse model of adolescent nephronophthisis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TNH6)
16. [Mutations in a novel gene, NPHP3, cause adolescent nephronophthisis, tapeto-retinal degeneration and hepatic fibrosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TNH6)
17. ensembl Release 106