# Myosin VIIA

> mammalian protein found in Mus musculus

**Wikidata**: [Q14914032](https://www.wikidata.org/wiki/Q14914032)  
**Source**: https://4ort.xyz/entity/myosin-viia-q14914032


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P97479)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97479)
5. [The giant spectrin βV couples the molecular motors to phototransduction and Usher syndrome type I proteins along their trafficking route](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97479)
6. [Shroom2, a myosin-VIIa- and actin-binding protein, directly interacts with ZO-1 at tight junctions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97479)
7. [PHR1, an integral membrane protein of the inner ear sensory cells, directly interacts with myosin 1c and myosin VIIa](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97479)
8. [PDZD7-MYO7A complex identified in enriched stereocilia membranes.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97479)
9. [Myosin XVa and whirlin, two deafness gene products required for hair bundle growth, are located at the stereocilia tips and interact directly](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97479)
10. [Physical and functional interaction between protocadherin 15 and myosin VIIa in mechanosensory hair cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97479)
11. [Interactions in the network of Usher syndrome type 1 proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97479)
12. [Molecular characterization of the ankle-link complex in cochlear hair cells and its role in the hair bundle functioning](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97479)
13. [FERM domain‐containing unconventional myosin VIIA interacts with integrin β5 subunit and regulates αvβ5‐mediated cell adhesion and migration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97479)
14. [The Usher 1B protein, MYO7A, is required for normal localization and function of the visual retinoid cycle enzyme, RPE65](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97479)
15. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97479&geneProductId=UniProtKB:P97479)
16. [Human Usher 1B/mouse shaker-1: the retinal phenotype discrepancy explained by the presence/absence of myosin VIIA in the photoreceptor cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97479)
17. [The role of Rab27a in the regulation of melanosome distribution within retinal pigment epithelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97479)
18. [Role of myosin VIIa and Rab27a in the motility and localization of RPE melanosomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97479)
19. [MyRIP, a novel Rab effector, enables myosin VIIa recruitment to retinal melanosomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97479)
20. [The small GTPase Rac1 regulates auditory hair cell morphogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97479&geneProductId=UniProtKB:P97479)
21. [Physical and functional interaction between protocadherin 15 and myosin VIIa in mechanosensory hair cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97479&geneProductId=UniProtKB:P97479)
22. [Myosin VIIa, harmonin and cadherin 23, three Usher I gene products that cooperate to shape the sensory hair cell bundle](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97479&geneProductId=UniProtKB:P97479)
23. [Myosin VIIa participates in opsin transport through the photoreceptor cilium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97479)
24. [Mutant myosin VIIa causes defective melanosome distribution in the RPE of shaker-1 mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97479)
25. [Expression in cochlea and retina of myosin VIIa, the gene product defective in Usher syndrome type 1B](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97479)
26. [Hes1 is a negative regulator of inner ear hair cell differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97479)
27. [A missense mutation in the previously undescribed gene Tmhs underlies deafness in hurry-scurry (hscy) mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97479)
28. [alphaII-betaV spectrin bridges the plasma membrane and cortical lattice in the lateral wall of the auditory outer hair cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97479)
29. [Conditional deletion of Atoh1 using Pax2-Cre results in viable mice without differentiated cochlear hair cells that have lost most of the organ of Corti.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97479)
30. [The small GTPase Rac1 regulates auditory hair cell morphogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97479)
31. [Notch inhibition induces mitotically generated hair cells in mammalian cochleae via activating the Wnt pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97479)
32. [Myosin VIIa, harmonin and cadherin 23, three Usher I gene products that cooperate to shape the sensory hair cell bundle](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97479)
33. [Class III myosins shape the auditory hair bundles by limiting microvilli and stereocilia growth](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97479)
34. [Origin of vestibular dysfunction in Usher syndrome type 1B](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97479)
35. [A core cochlear phenotype in USH1 mouse mutants implicates fibrous links of the hair bundle in its cohesion, orientation and differential growth](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97479)
36. [Cdh23 mutations in the mouse are associated with retinal dysfunction but not retinal degeneration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97479)
37. [The anatomy and development of the mutants pirouette, shaker-1 and waltzer in the mouse](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97479)
38. [The pattern of sensorineural degeneration in the cochlea of the deaf shaker-1 mouse: ultrastructural observations](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97479)
39. [HEARING DEGENERATION IN SHAKER-1 MOUSE. CORRELATION OF PHYSIOLOGICAL OBSERVATIONS WITH BEHAVIORAL RESPONSES AND WITH COCHLEAR ANATOMY](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97479)
40. [Defective myosin VIIA gene responsible for Usher syndrome type 1B](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97479)
41. [Shaker-1 mutations reveal roles for myosin VIIA in both development and function of cochlear hair cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97479)
42. [A type VII myosin encoded by the mouse deafness gene shaker-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97479)
43. [A forward genetics screen in mice identifies recessive deafness traits and reveals that pejvakin is essential for outer hair cell function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97479)
44. [Stereocilia defects in waltzer (Cdh23), shaker1 (Myo7a) and double waltzer/shaker1 mutant mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97479)
45. [A role for myosin VI in postsynaptic structure and glutamate receptor endocytosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97479)
46. [Mutation analysis of the mouse myosin VIIA deafness gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97479)
47. [Stereociliary myosin-1c receptors are sensitive to calcium chelation and absent from cadherin 23 mutant mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97479)
48. [Reduced climbing and increased slipping adaptation in cochlear hair cells of mice with Myo7a mutations](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97479)
49. [Abnormal phagocytosis by retinal pigmented epithelium that lacks myosin VIIa, the Usher syndrome 1B protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97479)
50. [A Myo7a mutation cosegregates with stereocilia defects and low-frequency hearing impairment](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97479)