# Myosin light chain 2

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21120852](https://www.wikidata.org/wiki/Q21120852)  
**Source**: https://4ort.xyz/entity/myosin-light-chain-2


## References

1. UniProt
2. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL4297517)
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P10916)
4. Q20641742
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10916)
6. [Familial hypertrophic cardiomyopathy mutations in the regulatory light chains of myosin affect their structure, Ca2+ binding, and phosphorylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10916)
7. [Different actin affinities of human cardiac essential myosin light chain isoforms](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10916)
8. [Interaction of a conserved peptide domain in recombinant human ventricular myosin light chain-2 with myosin heavy chain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10916)
9. [Protein interactions with myocilin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10916)
10. [The Tre2 oncoprotein, implicated in Ewing's sarcoma, interacts with two components of the cytoskeleton](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10916)
11. [Mutations in either the essential or regulatory light chains of myosin are associated with a rare myopathy in human heart and skeletal muscle](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10916)
12. [A cardiac myosin light chain kinase regulates sarcomere assembly in the vertebrate heart](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10916)
13. [Single-gene mutations and increased left ventricular wall thickness in the community: the Framingham Heart Study](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10916)
14. [Endosomes generate localized Rho-ROCK-MLC2-based contractile signals via Endo180 to promote adhesion disassembly](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10916)
15. [A novel phosphorylation site, Serine 199, in the C-terminus of cardiac troponin I regulates calcium sensitivity and susceptibility to calpain-induced proteolysis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10916)
16. [Identification of novel VHL target genes and relationship to hypoxic response pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10916)
17. ensembl Release 96