# Myocilin

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21150920](https://www.wikidata.org/wiki/Q21150920)  
**Source**: https://4ort.xyz/entity/myocilin-q21150920


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q99972)
3. Q20641742
4. [Myocilin is a modulator of Wnt signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99972)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99972)
6. [Protein interactions with myocilin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99972)
7. [Optimedin: a novel olfactomedin-related protein that interacts with myocilin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99972)
8. [Myocilin mediates myelination in the peripheral nervous system through ErbB2/3 signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99972)
9. [Interaction of recombinant myocilin with the matricellular protein SPARC: functional implications](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99972)
10. [In vitro localization of TIGR/MYOC in trabecular meshwork extracellular matrix and binding to fibronectin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99972)
11. [Mitochondrial association of myocilin, product of a glaucoma gene, in human trabecular meshwork cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99972)
12. [Glucocorticoid induction of the glaucoma gene MYOC in human and monkey trabecular meshwork cells and tissues](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99972)
13. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99972&geneProductId=UniProtKB:Q99972)
14. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99972&geneProductId=UniProtKB:Q99972)
15. [Protein profile of exosomes from trabecular meshwork cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99972&geneProductId=UniProtKB:Q99972)
16. [In vitro localization of TIGR/MYOC in trabecular meshwork extracellular matrix and binding to fibronectin](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99972&geneProductId=UniProtKB:Q99972)
17. [Localization of myocilin to the golgi apparatus in Schlemm's canal cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99972)
18. [Glaucoma-causing myocilin mutants require the Peroxisomal targeting signal-1 receptor (PTS1R) to elevate intraocular pressure](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99972)
19. [Protein profile of exosomes from trabecular meshwork cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99972)
20. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99972)
21. [Myocilin promotes substrate adhesion, spreading and formation of focal contacts in podocytes and mesangial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99972)
22. [Rho GTPase and cAMP/protein kinase A signaling mediates myocilin-induced alterations in cultured human trabecular meshwork cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99972)
23. [Myocilin, a glaucoma-associated protein, promotes cell migration through activation of integrin-focal adhesion kinase-serine/threonine kinase signaling pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99972)
24. [Myocilin stimulates osteogenic differentiation of mesenchymal stem cells through mitogen-activated protein kinase signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99972)
25. [Differential effects of myocilin and optineurin, two glaucoma genes, on neurite outgrowth](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99972)
26. Ensembl Release 99