# Myeloid cell leukemia sequence 1

> mammalian protein found in Mus musculus

**Wikidata**: [Q21428169](https://www.wikidata.org/wiki/Q21428169)  
**Source**: https://4ort.xyz/entity/myeloid-cell-leukemia-sequence-1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P97287)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97287)
5. [Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97287)
6. [Pro-apoptotic activity of inhibitory PAS domain protein (IPAS), a negative regulator of HIF-1, through binding to pro-survival Bcl-2 family proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97287)
7. [BOK Is a Non-canonical BCL-2 Family Effector of Apoptosis Regulated by ER-Associated Degradation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97287)
8. [The fast-mobility isoform of mouse Mcl-1 is a mitochondrial matrix-localized protein with attenuated anti-apoptotic activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97287)
9. [Prevention of cytokine withdrawal-induced apoptosis by Mcl-1 requires interaction between Mcl-1 and Bim](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97287)
10. [Structural insights into the degradation of Mcl-1 induced by BH3 domains](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97287)
11. [Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97287)
12. [Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97287)
13. [Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97287)
14. [BH3 domains other than Bim and Bid can directly activate Bax/Bak](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97287)
15. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97287)
16. [ATM-dependent expression of IEX-1 controls nuclear accumulation of Mcl-1 and the DNA damage response](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97287)
17. [The intracellular distribution and pattern of expression of Mcl-1 overlap with, but are not identical to, those of Bcl-2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97287)
18. [The fast-mobility isoform of mouse Mcl-1 is a mitochondrial matrix-localized protein with attenuated anti-apoptotic activity](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97287&geneProductId=UniProtKB:P97287)
19. [Parkin-dependent degradation of the F-box protein Fbw7β promotes neuronal survival in response to oxidative stress by stabilizing Mcl-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97287)
20. [Goofy Coordinates the Acuity of Olfactory Signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97287)
21. [The apoptosis and proliferation of SAC-activated B cells by IL-10 are associated with changes in Bcl-2, Bcl-xL, and Mcl-1 expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97287)
22. [MCL-1V, a novel mouse antiapoptotic MCL-1 variant, generated by RNA splicing at a non-canonical splicing pair](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97287&geneProductId=UniProtKB:P97287)
23. [Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97287&geneProductId=UniProtKB:P97287)
24. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97287&geneProductId=UniProtKB:P97287)
25. [Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97287&geneProductId=UniProtKB:P97287)
26. [Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97287&geneProductId=UniProtKB:P97287)
27. ensembl Release 106