# Msh homeobox 2

> mammalian protein found in Mus musculus

**Wikidata**: [Q21985711](https://www.wikidata.org/wiki/Q21985711)  
**Source**: https://4ort.xyz/entity/msh-homeobox-2


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q03358)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03358)
5. [Structure−Function Analysis of Msx2-Mediated Transcriptional Suppression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03358)
6. [Comparison of MSX-1 and MSX-2 suggests a molecular basis for functional redundancy](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03358&geneProductId=UniProtKB:Q03358)
7. [Structure−Function Analysis of Msx2-Mediated Transcriptional Suppression](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03358&geneProductId=UniProtKB:Q03358)
8. [The Canonical BMP Signaling Pathway Plays a Crucial Part in Stimulation of Dentin Sialophosphoprotein Expression by BMP-2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03358)
9. [The RRM domain of MINT, a novel Msx2 binding protein, recognizes and regulates the rat osteocalcin promoter](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03358)
10. [A RING finger protein Praja1 regulates Dlx5-dependent transcription through its ubiquitin ligase activity for the Dlx/Msx-interacting MAGE/Necdin family protein, Dlxin-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03358)
11. [Dlxin-1, a novel protein that binds Dlx5 and regulates its transcriptional function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03358)
12. [Necdin interacts with the Msx2 homeodomain protein via MAGE-D1 to promote myogenic differentiation of C2C12 cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03358)
13. [Comparison of MSX-1 and MSX-2 suggests a molecular basis for functional redundancy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03358)
14. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03358&geneProductId=UniProtKB:Q03358)
15. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03358)
16. [Syndactyly and preaxial synpolydactyly in the single Sfrp2 deleted mutant mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03358)
17. [Msx1 and Msx2 promote meiosis initiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03358)
18. [Reciprocal roles of MSX2 in regulation of osteoblast and adipocyte differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03358)
19. [Accelerated closure of skin wounds in mice deficient in the homeobox gene Msx2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03358)
20. [Msx2 deficiency in mice causes pleiotropic defects in bone growth and ectodermal organ formation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03358)
21. [Msx1 and Msx2 are required for endothelial-mesenchymal transformation of the atrioventricular cushions and patterning of the atrioventricular myocardium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03358)
22. [Comparative analysis of TGF beta s, BMPs, IGF1, msxs, fibronectin, osteonectin and bone sialoprotein gene expression during normal and in vitro-induced odontoblast differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03358)
23. [Regulation of Msx-1, Msx-2, Bmp-2 and Bmp-4 during foetal and postnatal mammary gland development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03358)
24. [Concerted action of Msx1 and Msx2 in regulating cranial neural crest cell differentiation during frontal bone development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03358)
25. [Msx1 and Msx2 regulate survival of secondary heart field precursors and post-migratory proliferation of cardiac neural crest in the outflow tract](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03358)
26. [Msx1 and Msx2 in limb mesenchyme modulate digit number and identity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03358)
27. [FKBP8 cell-autonomously controls neural tube patterning through a Gli2- and Kif3a-dependent mechanism](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03358)
28. [Msx genes are important apoptosis effectors downstream of the Shh/Gli3 pathway in the limb](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03358)
29. [Analysis of Msx1; Msx2 double mutants reveals multiple roles for Msx genes in limb development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03358)
30. [Bone morphogenetic protein-2-induced alkaline phosphatase expression is stimulated by Dlx5 and repressed by Msx2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03358)
31. [Msx1 and Msx2 are functional interacting partners of T-box factors in the regulation of Connexin43](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03358)
32. [Bone morphogenetic protein-induced MSX1 and MSX2 inhibit myocardin-dependent smooth muscle gene transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03358)
33. [Msx2 is a repressor of chondrogenic differentiation in migratory cranial neural crest cells†](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03358)
34. ensembl Release 106