# MRX complex DNA-binding subunit YNL250W

> fungal protein found in Saccharomyces cerevisiae S288c

**Wikidata**: [Q27547991](https://www.wikidata.org/wiki/Q27547991)  
**Source**: https://4ort.xyz/entity/mrx-complex-dna-binding-subunit-ynl250w


## References

1. UniProt
2. Q20641742
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P12753)
4. [Superfamily of UvrA-related NTP-binding proteins. Implications for rational classification of recombination/repair systems](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12753)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12753)
6. [Effect of amino acid substitutions in the rad50 ATP binding domain on DNA double strand break repair in yeast](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12753)
7. [The characterization of Saccharomyces cerevisiae Mre11/Rad50/Xrs2 complex reveals that Rad50 negatively regulates Mre11 endonucleolytic but not the exonucleolytic activity](http://www.ebi.ac.uk/QuickGO/annotations?protein=P12753&geneProductId=UniProtKB:P12753)
8. [Late S phase-specific recruitment of Mre11 complex triggers hierarchical assembly of telomere replication proteins in Saccharomyces cerevisiae.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12753)
9. [Rad50 adenylate kinase activity regulates DNA tethering by Mre11/Rad50 complexes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P12753&geneProductId=UniProtKB:P12753)
10. [RAD50 protein of S.cerevisiae exhibits ATP-dependent DNA binding](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12753)
11. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12753)
12. [Mechanism of the ATP-dependent DNA end-resection machinery from Saccharomyces cerevisiae.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12753)
13. [Complex formation and functional versatility of Mre11 of budding yeast in recombination](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12753)
14. [Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12753)
15. [Structure of Mre11–Nbs1 complex yields insights into ataxia-telangiectasia–like disease mutations and DNA damage signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12753)
16. [Antiviral protein Ski8 is a direct partner of Spo11 in meiotic DNA break formation, independent of its cytoplasmic role in RNA metabolism](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12753)
17. [Sae2 promotes dsDNA endonuclease activity within Mre11–Rad50–Xrs2 to resect DNA breaks](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12753)
18. [Tel1 and Rif2 Regulate MRX Functions in End-Tethering and Repair of DNA Double-Strand Breaks](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12753)
19. [DNA end recognition by the Mre11 nuclease dimer: insights into resection and repair of damaged DNA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12753)
20. [The Rad50 coiled-coil domain is indispensable for Mre11 complex functions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12753)
21. [The characterization of Saccharomyces cerevisiae Mre11/Rad50/Xrs2 complex reveals that Rad50 negatively regulates Mre11 endonucleolytic but not the exonucleolytic activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12753)
22. [Rad50 adenylate kinase activity regulates DNA tethering by Mre11/Rad50 complexes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12753)
23. [Complex formation and functional versatility of Mre11 of budding yeast in recombination](http://www.ebi.ac.uk/QuickGO/annotations?protein=P12753&geneProductId=UniProtKB:P12753)
24. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P12753&geneProductId=UniProtKB:P12753)
25. [Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12753)
26. [Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12753)
27. [The proteome of Saccharomyces cerevisiae mitochondria](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12753)
28. [Two survivor pathways that allow growth in the absence of telomerase are generated by distinct telomere recombination events](http://www.ebi.ac.uk/QuickGO/annotations?protein=P12753&geneProductId=UniProtKB:P12753)
29. [Break-induced replication: a review and an example in budding yeast](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12753)
30. [Meiotic chromosomes: it takes two to tango](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12753)
31. [Mitochondrial Genome Maintenance: Roles for Nuclear Nonhomologous End-Joining Proteins in Saccharomyces cerevisiae](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12753)
32. [Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12753)
33. [A genomics-based screen for yeast mutants with an altered recombination/end-joining repair ratio.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12753)
34. [A novel function for the Mre11-Rad50-Xrs2 complex in base excision repair](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12753)
35. [The Saccharomyces cerevisiae Mre11-Rad50-Xrs2 complex promotes trinucleotide repeat expansions independently of homologous recombination.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12753)
36. [Two survivor pathways that allow growth in the absence of telomerase are generated by distinct telomere recombination events](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12753)
37. ensembl Release 106