# Mothers against dpp Dmel_CG12399

> protein found in Drosophila melanogaster

**Wikidata**: [Q29820402](https://www.wikidata.org/wiki/Q29820402)  
**Source**: https://4ort.xyz/entity/mothers-against-dpp-dmel-cg12399


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P42003)
3. Q20641742
4. [Smad proteins act in combination with synergistic and antagonistic regulators to target Dpp responses to the Drosophila mesoderm](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42003&geneProductId=UniProtKB:P42003)
5. [The zinc finger protein schnurri acts as a Smad partner in mediating the transcriptional response to decapentaplegic.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42003&geneProductId=UniProtKB:P42003)
6. [Signal transduction of the TGF-beta superfamily by Smad proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42003&geneProductId=UniProtKB:P42003)
7. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42003&geneProductId=UniProtKB:P42003)
8. [Comparative gene expression analysis of Dtg, a novel target gene of Dpp signaling pathway in the early Drosophila melanogaster embryo](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42003&geneProductId=UniProtKB:P42003)
9. [Drosophila Mad binds to DNA and directly mediates activation of vestigial by Decapentaplegic](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42003&geneProductId=UniProtKB:P42003)
10. [The DSmurf ubiquitin-protein ligase restricts BMP signaling spatially and temporally during Drosophila embryogenesis.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42003&geneProductId=UniProtKB:P42003)
11. [dSmurf Selectively Degrades Decapentaplegic-activated MAD, and Its Overexpression Disrupts Imaginal Disc Development](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42003&geneProductId=UniProtKB:P42003)
12. [Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-beta pathways](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42003&geneProductId=UniProtKB:P42003)
13. [Lissencephaly-1 controls germline stem cell self-renewal through modulating bone morphogenetic protein signaling and niche adhesion](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42003&geneProductId=UniProtKB:P42003)
14. [Medea is a Drosophila Smad4 homolog that is differentially required to potentiate DPP responses](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42003&geneProductId=UniProtKB:P42003)
15. [Drosophila TGIF proteins are transcriptional activators](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42003&geneProductId=UniProtKB:P42003)
16. [Threshold response of C15 to the Dpp gradient in Drosophila is established by the cumulative effect of Smad and Zen activators and negative cues](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42003&geneProductId=UniProtKB:P42003)
17. [A conserved activation element in BMP signaling during Drosophila development](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42003&geneProductId=UniProtKB:P42003)
18. [Tgfβ signaling acts on a Hox response element to confer specificity and diversity to Hox protein function](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42003&geneProductId=UniProtKB:P42003)
19. [Nuclear interpretation of Dpp signaling in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42003&geneProductId=UniProtKB:P42003)
20. [Drosophila nucleoporin Nup154 controls cell viability, proliferation and nuclear accumulation of Mad transcription factor.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42003&geneProductId=UniProtKB:P42003)
21. [Identification of phosphatases for Smad in the BMP/DPP pathway](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42003&geneProductId=UniProtKB:P42003)
22. [Fragile X mental retardation protein regulates trans-synaptic signaling inDrosophila](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42003&geneProductId=UniProtKB:P42003)
23. [Mothers against dpp encodes a conserved cytoplasmic protein required in DPP/TGF-beta responsive cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42003&geneProductId=UniProtKB:P42003)
24. [Dynamic decapentaplegic signaling regulates patterning and adhesion in the Drosophila pupal retina](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42003&geneProductId=UniProtKB:P42003)
25. [Conservation and Divergence in Molecular Mechanisms of Axis Formation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42003&geneProductId=UniProtKB:P42003)
26. [Mad acts downstream of Dpp receptors, revealing a differential requirement for dpp signaling in initiation and propagation of morphogenesis in the Drosophila eye.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42003&geneProductId=UniProtKB:P42003)
27. [Signaling pathways directing the movement and fusion of epithelial sheets: lessons from dorsal closure in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42003&geneProductId=UniProtKB:P42003)
28. [Novel Genes Involved in Controlling Specification of Drosophila FMRFamide Neuropeptide Cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42003&geneProductId=UniProtKB:P42003)
29. [Branching morphogenesis of the Drosophila tracheal system.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42003&geneProductId=UniProtKB:P42003)
30. [Epidermal growth factor receptor and transforming growth factor-beta signaling contributes to variation for wing shape in Drosophila melanogaster](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42003&geneProductId=UniProtKB:P42003)
31. [Transgenic analysis of the Smad family of TGF-beta signal transducers in Drosophila melanogaster suggests new roles and new interactions between family members](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42003&geneProductId=UniProtKB:P42003)
32. [Dpp signaling directs cell motility and invasiveness during epithelial morphogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42003&geneProductId=UniProtKB:P42003)
33. [Control of cardiac development by an evolutionarily conserved transcriptional network](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42003&geneProductId=UniProtKB:P42003)
34. [Regulation of the retinal determination gene dachshund in the embryonic head and developing eye of Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42003&geneProductId=UniProtKB:P42003)
35. [Integration of epithelial patterning and morphogenesis in Drosophila ovarian follicle cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42003&geneProductId=UniProtKB:P42003)
36. [BMP signaling is required for controlling somatic stem cell self-renewal in the Drosophila ovary](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42003&geneProductId=UniProtKB:P42003)
37. [decapentaplegic Is Essential for the Maintenance and Division of Germline Stem Cells in the Drosophila Ovary](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42003&geneProductId=UniProtKB:P42003)
38. [Mad is required for wingless signaling in wing development and segment patterning in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42003&geneProductId=UniProtKB:P42003)
39. [The stem-cell niche theory: lessons from flies](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42003&geneProductId=UniProtKB:P42003)
40. [A transient niche regulates the specification of Drosophila intestinal stem cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42003&geneProductId=UniProtKB:P42003)
41. [Organ formation in Drosophila: specification and morphogenesis of the salivary gland.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42003&geneProductId=UniProtKB:P42003)
42. [Nemo kinase interacts with Mad to coordinate synaptic growth at the Drosophila neuromuscular junction](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42003&geneProductId=UniProtKB:P42003)
43. [Highwire regulates presynaptic BMP signaling essential for synaptic growth.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42003&geneProductId=UniProtKB:P42003)
44. [dAcsl, the Drosophila ortholog of acyl-CoA synthetase long-chain family member 3 and 4, inhibits synapse growth by attenuating bone morphogenetic protein signaling via endocytic recycling.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42003&geneProductId=UniProtKB:P42003)
45. [The role of Dpp signaling in maintaining the Drosophila anteroposterior compartment boundary](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42003&geneProductId=UniProtKB:P42003)
46. [Postsynaptic glutamate receptors regulate local BMP signaling at theDrosophilaneuromuscular junction](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42003&geneProductId=UniProtKB:P42003)
47. [Injury-induced BMP signaling negatively regulates Drosophila midgut homeostasis.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42003&geneProductId=UniProtKB:P42003)
48. [Hemocyte-secreted type IV collagen enhances BMP signaling to guide renal tubule morphogenesis in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42003&geneProductId=UniProtKB:P42003)
49. [Extracellular signals responsible for spatially regulated proliferation in the differentiating Drosophila eye.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42003&geneProductId=UniProtKB:P42003)
50. ensembl Release 106