# Moesin

> mammalian protein found in Homo sapiens

**Wikidata**: [Q3860053](https://www.wikidata.org/wiki/Q3860053)  
**Source**: https://4ort.xyz/entity/moesin-q3860053


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P26038)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038)
5. [Moesin: a member of the protein 4.1-talin-ezrin family of proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038)
6. [The TSC1 tumour suppressor hamartin regulates cell adhesion through ERM proteins and the GTPase Rho](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038)
7. [Podoplanin binds ERM proteins to activate RhoA and promote epithelial-mesenchymal transition.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038)
8. [Ezrin has properties to self-associate at the plasma membrane](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038)
9. [TIMAP is a positive regulator of pulmonary endothelial barrier function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038)
10. [The ERM proteins interact with the HOPS complex to regulate the maturation of endosomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038)
11. [The Nck-interacting kinase phosphorylates ERM proteins for formation of lamellipodium by growth factors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038)
12. [The EBP50-moesin interaction involves a binding site regulated by direct masking on the FERM domain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038)
13. [Role of moesin in hyaluronan induced cell migration in glioblastoma multiforme](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038)
14. [Structural model of the dimeric Parkinson's protein LRRK2 reveals a compact architecture involving distant interdomain contacts](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038)
15. [14-3-3 binding to LRRK2 is disrupted by multiple Parkinson's disease-associated mutations and regulates cytoplasmic localization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038)
16. [GTPase activity and neuronal toxicity of Parkinson's disease-associated LRRK2 is regulated by ArfGAP1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038)
17. [Parkinson-related LRRK2 mutation R1441C/G/H impairs PKA phosphorylation of LRRK2 and disrupts its interaction with 14-3-3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038)
18. [NHE-RF, a Regulatory Cofactor for Na+-H+Exchange, Is a Common Interactor for Merlin and ERM (MERM) Proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038)
19. [LRRK2 kinase activity and biology are not uniformly predicted by its autophosphorylation and cellular phosphorylation site status](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038)
20. [Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038)
21. [Biochemical characterization of highly purified leucine-rich repeat kinases 1 and 2 demonstrates formation of homodimers](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038)
22. [LRRK2 kinase activity regulates synaptic vesicle trafficking and neurotransmitter release through modulation of LRRK2 macro-molecular complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038)
23. [GTPase activity regulates kinase activity and cellular phenotypes of Parkinson's disease-associated LRRK2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038)
24. [A Parkinson's disease gene regulatory network identifies the signaling protein RGS2 as a modulator of LRRK2 activity and neuronal toxicity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038)
25. [The Parkinson Disease-linked LRRK2 Protein Mutation I2020T Stabilizes an Active State Conformation Leading to Increased Kinase Activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038)
26. [Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038)
27. [Raftlin Is Involved in the Nucleocapture Complex to Induce Poly(I:C)-mediated TLR3 Activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038)
28. [Modulated interaction of the ERM protein, moesin, with CD93](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038)
29. [LOK is a major ERM kinase in resting lymphocytes and regulates cytoskeletal rearrangement through ERM phosphorylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038)
30. [Dynamic interaction of VCAM-1 and ICAM-1 with moesin and ezrin in a novel endothelial docking structure for adherent leukocytes.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038)
31. [Group A streptococcal surface GAPDH, SDH, recognizes uPAR/CD87 as its receptor on the human pharyngeal cell and mediates bacterial adherence to host cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038)
32. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P26038&geneProductId=UniProtKB:P26038)
33. [Dynamic proteomics in individual human cells uncovers widespread cell-cycle dependence of nuclear proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=P26038&geneProductId=UniProtKB:P26038)
34. [Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense](http://www.ebi.ac.uk/QuickGO/annotations?protein=P26038&geneProductId=UniProtKB:P26038)
35. [Testosterone promotes vascular endothelial cell migration via upregulation of ROCK-2/moesin cascade](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038)
36. [Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability](http://www.ebi.ac.uk/QuickGO/annotations?protein=P26038&geneProductId=UniProtKB:P26038)
37. [Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P26038&geneProductId=UniProtKB:P26038)
38. [A novel role for BRCA1 in regulating breast cancer cell spreading and motility](http://www.ebi.ac.uk/QuickGO/annotations?protein=P26038&geneProductId=UniProtKB:P26038)
39. [Structure and localization on the X chromosome of the gene coding for the human filopodial protein moesin (MSN)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038)
40. [Dynamic interaction of VCAM-1 and ICAM-1 with moesin and ezrin in a novel endothelial docking structure for adherent leukocytes.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P26038&geneProductId=UniProtKB:P26038)
41. [NHERF1/EBP50 controls morphogenesis of 3D colonic glands by stabilizing PTEN and ezrin-radixin-moesin proteins at the apical membrane](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038)
42. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P26038&geneProductId=UniProtKB:P26038)
43. [Protein profile of exosomes from trabecular meshwork cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P26038&geneProductId=UniProtKB:P26038)
44. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P26038&geneProductId=UniProtKB:P26038)
45. [MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P26038&geneProductId=UniProtKB:P26038)
46. [Proteomic and biochemical analyses of human B cell-derived exosomes. Potential implications for their function and multivesicular body formation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P26038&geneProductId=UniProtKB:P26038)
47. [Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)](http://www.ebi.ac.uk/QuickGO/annotations?protein=P26038&geneProductId=UniProtKB:P26038)
48. [Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038)
49. [Adaptor protein cerebral cavernous malformation 3 (CCM3) mediates phosphorylation of the cytoskeletal proteins ezrin/radixin/moesin by mammalian Ste20-4 to protect cells from oxidative stress](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26038)
50. [Human colostrum: identification of minor proteins in the aqueous phase by proteomics](http://www.ebi.ac.uk/QuickGO/annotations?protein=P26038&geneProductId=UniProtKB:P26038)