# Mitogen-activated protein kinase kinase kinase kinase STE20 YHL007C

> fungal protein found in Saccharomyces cerevisiae S288c

**Wikidata**: [Q27553030](https://www.wikidata.org/wiki/Q27553030)  
**Source**: https://4ort.xyz/entity/mitogen-activated-protein-kinase-kinase-kinase-kinase-ste20-yhl007c


## References

1. UniProt
2. Q20641742
3. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03497&geneProductId=UniProtKB:Q03497)
4. [Molecular characterization of Ste20p, a potential mitogen-activated protein or extracellular signal-regulated kinase kinase (MEK) kinase kinase from Saccharomyces cerevisiae.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03497&geneProductId=UniProtKB:Q03497)
5. [Sterile 20 kinase phosphorylates histone H2B at serine 10 during hydrogen peroxide-induced apoptosis in S. cerevisiae](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03497&geneProductId=UniProtKB:Q03497)
6. [Interaction of a G-protein beta-subunit with a conserved sequence in Ste20/PAK family protein kinases.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03497&geneProductId=UniProtKB:Q03497)
7. [Role for the Rho-family GTPase Cdc42 in yeast mating-pheromone signal pathway.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03497&geneProductId=UniProtKB:Q03497)
8. [Modulation of sterol homeostasis by the Cdc42p effectors Cla4p and Ste20p in the yeast Saccharomyces cerevisiae](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03497&geneProductId=UniProtKB:Q03497)
9. [Cdc42 regulation of kinase activity and signaling by the yeast p21-activated kinase Ste20.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03497&geneProductId=UniProtKB:Q03497)
10. [Proteome-wide protein interaction measurements of bacterial proteins of unknown function](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03497&geneProductId=UniProtKB:Q03497)
11. [An in vivo map of the yeast protein interactome](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03497&geneProductId=UniProtKB:Q03497)
12. [Interaction with the SH3 domain protein Bem1 regulates signaling by the Saccharomyces cerevisiae p21-activated kinase Ste20](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03497&geneProductId=UniProtKB:Q03497)
13. [Structure-templated predictions of novel protein interactions from sequence information](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03497&geneProductId=UniProtKB:Q03497)
14. [Bayesian modeling of the yeast SH3 domain interactome predicts spatiotemporal dynamics of endocytosis proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03497&geneProductId=UniProtKB:Q03497)
15. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03497&geneProductId=UniProtKB:Q03497)
16. [The Cdc42 effectors Ste20, Cla4, and Skm1 down-regulate the expression of genes involved in sterol uptake by a mitogen-activated protein kinase-independent pathway](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03497&geneProductId=UniProtKB:Q03497)
17. [Functional analysis of the interaction between the small GTP binding protein Cdc42 and the Ste20 protein kinase in yeast](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03497&geneProductId=UniProtKB:Q03497)
18. [Global analysis of yeast mRNPs](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03497&geneProductId=UniProtKB:Q03497)
19. [Dcp2 phosphorylation by Ste20 modulates stress granule assembly and mRNA decay in Saccharomyces cerevisiae](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03497&geneProductId=UniProtKB:Q03497)
20. [A role for cell polarity proteins in mitotic exit](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03497&geneProductId=UniProtKB:Q03497)
21. [Yeast Cdc42 GTPase and Ste20 PAK-like kinase regulate Sho1-dependent activation of the Hog1 MAPK pathway.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03497&geneProductId=UniProtKB:Q03497)
22. [Polarized growth controls cell shape and bipolar bud site selection in Saccharomyces cerevisiae](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03497&geneProductId=UniProtKB:Q03497)
23. [Heat stress activates the yeast high-osmolarity glycerol mitogen-activated protein kinase pathway, and protein tyrosine phosphatases are essential under heat stress](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03497&geneProductId=UniProtKB:Q03497)
24. [Elements of the yeast pheromone response pathway required for filamentous growth of diploids](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03497&geneProductId=UniProtKB:Q03497)
25. [Elements of a single MAP kinase cascade in Saccharomyces cerevisiae mediate two developmental programs in the same cell type: mating and invasive growth](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03497&geneProductId=UniProtKB:Q03497)
26. [The protein kinase homologue Ste20p is required to link the yeast pheromone response G-protein beta gamma subunits to downstream signalling components](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03497&geneProductId=UniProtKB:Q03497)
27. [p21-activated kinases Cla4 and Ste20 regulate vacuole inheritance in Saccharomyces cerevisiae](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03497&geneProductId=UniProtKB:Q03497)
28. ensembl Release 106