Mitogen-activated protein kinase kinase kinase kinase 3
type: Thing
description: mammalian protein found in Mus musculus
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P279
  value: protein
additional property: PropertyValue
  property ID: P361
  value: mitogen-activated protein (MAP) kinase kinase kinase kinase
additional property: PropertyValue
  property ID: P361
  value: Protein kinase-like domain superfamily
additional property: PropertyValue
  property ID: P361
  value: Citron homology (CNH) domain, protein family
additional property: PropertyValue
  property ID: P527
  value: Citron homology (CNH) domain
additional property: PropertyValue
  property ID: P527
  value: protein kinase domain
additional property: PropertyValue
  property ID: P527
  value: protein kinase, ATP binding site
additional property: PropertyValue
  property ID: P637
  value: NP_001277274
additional property: PropertyValue
  property ID: P637
  value: XP_006524255
additional property: PropertyValue
  property ID: P637
  value: XP_006524259
additional property: PropertyValue
  property ID: P680
  value: transferase activity
additional property: PropertyValue
  property ID: P680
  value: nucleotide binding
additional property: PropertyValue
  property ID: P680
  value: protein kinase activity
additional property: PropertyValue
  property ID: P681
  value: cytoplasm
additional property: PropertyValue
  property ID: P682
  value: response to tumor necrosis factor
additional property: PropertyValue
  property ID: P682
  value: protein phosphorylation
additional property: PropertyValue
  property ID: P682
  value: intracellular signal transduction
additional property: PropertyValue
  property ID: P702
  value: Map4k3
additional property: PropertyValue
  property ID: P703
  value: house mouse
additional property: PropertyValue
  property ID: P705
  value: ENSMUSP00000025089
additional property: PropertyValue
  property ID: P705
  value: ENSMUSP00000108008
additional property: PropertyValue
  property ID: P705
  value: ENSMUSP00000157308
confidence:
  popularity graph score:
    score: 0.001
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 8
      unique citations norm: 0.003
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 8
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P279:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: Q99JP0
    source count: 1
    confidence: 0.2
  P361:
    value: Q24739489
    source count: 1
    confidence: 0.2
    value label: mitogen-activated protein (MAP) kinase kinase kinase kinase
  P361:
    value: Q24726164
    source count: 1
    confidence: 0.2
    value label: Protein kinase-like domain superfamily
  P361:
    value: Q83140881
    source count: 1
    confidence: 0.2
    value label: Citron homology (CNH) domain, protein family
  P361:
    value: Q83138186
    source count: 1
    confidence: 0.2
    value label: Protein kinase domain, protein family
  P361:
    value: Q95354221
    source count: 1
    confidence: 0.2
    value label: Protein kinase, ATP binding site, protein family
  P527:
    value: Q24773095
    source count: 1
    confidence: 0.2
    value label: Citron homology (CNH) domain
  P527:
    value: Q24768234
    source count: 1
    confidence: 0.2
    value label: protein kinase domain
  P527:
    value: Q24769051
    source count: 1
    confidence: 0.2
    value label: protein kinase, ATP binding site
  P637:
    value: NP_001277274
    source count: 1
    confidence: 0.2
  P637:
    value: XP_006524255
    source count: 1
    confidence: 0.2
  P637:
    value: XP_006524259
    source count: 1
    confidence: 0.2
  P637:
    value: XP_006524260
    source count: 1
    confidence: 0.2
  P637:
    value: NP_001347207
    source count: 1
    confidence: 0.2
  P680:
    value: Q14840131
    source count: 1
    confidence: 0.2
    value label: transferase activity
  P680:
    value: Q14860365
    source count: 1
    confidence: 0.2
    value label: nucleotide binding
  P680:
    value: Q14820641
    source count: 1
    confidence: 0.2
    value label: protein kinase activity
  P680:
    value: Q14326094
    source count: 4
    confidence: 0.8
    value label: protein serine/threonine kinase activity
  P680:
    value: Q14817981
    source count: 5
    confidence: 1.0
    value label: ATP binding
  P681:
    value: Q79899
    source count: 1
    confidence: 0.2
    value label: cytoplasm
  P682:
    value: Q14599713
    source count: 2
    confidence: 0.4
    value label: response to tumor necrosis factor
  P682:
    value: Q7251493
    source count: 4
    confidence: 0.8
    value label: protein phosphorylation

value: Q14851952
source count: 3
confidence: 0.6
value label: intracellular signal transduction

value: Q14818114
source count: 3
confidence: 0.6
value label: response to UV

value: Q242736
source count: 1
confidence: 0.2
value label: phosphorylation

value: Q18297270
source count: 1
confidence: 0.2
value label: Map4k3

value: Q83310
source count: 1
confidence: 0.2
value label: house mouse

value: ENSMUSP00000025089
source count: 1
confidence: 0.2

value: ENSMUSP00000108008
source count: 1
confidence: 0.2

value: ENSMUSP00000157308
source count: 1
confidence: 0.2

source: GOA
stated in qid: Q28018111
retrieved: 2019-02-14

source: GOA
stated in qid: Q28018111
retrieved: 2018-04-24

source: The kinase GLK controls autoimmunity and NF-κB signaling by activating the kinase PKC-θ in T cells
stated in qid: Q24339510
retrieved: 2019-02-14

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2019-02-14

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2022-05-25

source: Q20641742
stated in qid: Q20641742
retrieved: 2022-03-20

source: ensembl Release 106
stated in qid: Q111699881

wikidata id: Q21984349
domain: protein
level: standard
html url: https://4ort.xyz/entity/mitogen-activated-protein-kinase-kinase-kinase-kinase-3-q21984349
markdown url: https://4ort.xyz/entity/mitogen-activated-protein-kinase-kinase-kinase-kinase-3-q21984349.md
facts url summary: https://4ort.xyz/entity/mitogen-activated-protein-kinase-kinase-kinase-kinase-3-q21984349/facts.json
facts url standard: https://4ort.xyz/entity/mitogen-activated-protein-kinase-kinase-kinase-kinase-3-q21984349/facts.json
facts url full: https://4ort.xyz/entity/mitogen-activated-protein-kinase-kinase-kinase-kinase-3-q21984349/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-06T21:44:47.756464Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T14:12:27.636059+00:00Z