# mitogen-activated protein kinase kinase 7

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21109744](https://www.wikidata.org/wiki/Q21109744)  
**Source**: https://4ort.xyz/entity/mitogen-activated-protein-kinase-kinase-7-q21109744


## References

1. UniProt
2. IUPHAR/BPS Guide to PHARMACOLOGY
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O14733)
4. Q20641742
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14733)
6. [SP3 acts as a positive regulator on the core promoter of human ZPK gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14733)
7. [Human Mitogen-activated Protein Kinase Kinase 7 (MKK7) Is a Highly Conserved c-Jun N-terminal Kinase/Stress-activated Protein Kinase (JNK/SAPK) Activated by Environmental Stresses and Physiological Stimuli](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14733)
8. [Angiotensin-converting enzyme is involved in outside-in signaling in endothelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14733)
9. [Human tribbles, a protein family controlling mitogen-activated protein kinase cascades](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14733)
10. [Using an in Situ Proximity Ligation Assay to Systematically Profile Endogenous Protein–Protein Interactions in a Pathway Network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14733)
11. [Vaccinia virus B1R kinase interacts with JIP1 and modulates c-Jun-dependent signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14733)
12. [MKK6 binds and regulates expression of Parkinson's disease-related protein LRRK2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14733)
13. [An antiapoptotic protein, c-FLIPL, directly binds to MKK7 and inhibits the JNK pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14733)
14. [Cancer-selective targeting of the NF-κB survival pathway with GADD45β/MKK7 inhibitors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14733)
15. [Naturally occurring neomorphic PIK3R1 mutations activate the MAPK pathway, dictating therapeutic response to MAPK pathway inhibitors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14733)
16. [Vaccinia-related kinase 2 modulates the stress response to hypoxia mediated by TAK1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14733)
17. [Modulation of interleukin-1 transcriptional response by the interaction between VRK2 and the JIP1 scaffold protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14733)
18. [Human Mitogen-activated Protein Kinase Kinase 7 (MKK7) Is a Highly Conserved c-Jun N-terminal Kinase/Stress-activated Protein Kinase (JNK/SAPK) Activated by Environmental Stresses and Physiological Stimuli](http://www.ebi.ac.uk/QuickGO/annotations?protein=O14733&geneProductId=UniProtKB:O14733)
19. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14733)
20. [High-throughput RNAi screening reveals novel regulators of telomerase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14733)
21. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O14733&geneProductId=UniProtKB:O14733)
22. [ApoE2, ApoE3, and ApoE4 Differentially Stimulate APP Transcription and Aβ Secretion](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14733)
23. Ensembl Release 99
24. UMLS 2023