# Mitogen activated protein kinase kinase 5

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28560156](https://www.wikidata.org/wiki/Q28560156)  
**Source**: https://4ort.xyz/entity/mitogen-activated-protein-kinase-kinase-5-q28560156


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q62862)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62862)
5. [Isolation of MEK5 and differential expression of alternatively spliced forms](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62862)
6. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62862)
7. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62862&geneProductId=UniProtKB:Q62862)
8. [MEK5 and ERK5 are localized in the nuclei of resting as well as stimulated cells, while MEKK2 translocates from the cytosol to the nucleus upon stimulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62862)
9. [Erk5 activation elicits a vasoprotective endothelial phenotype via induction of Kruppel-like factor 4 (KLF4)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62862)
10. [Hypertrophic responses to cardiotrophin-1 are not mediated by STAT3, but via a MEK5-ERK5 pathway in cultured cardiomyocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62862)
11. [Activation of the MEK5/ERK5 cascade is responsible for biliary dysgenesis in a rat model of Caroli's disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62862)
12. ensembl Release 106