# Mitogen-activated protein kinase kinase 1

> mammalian protein found in Mus musculus

**Wikidata**: [Q21984423](https://www.wikidata.org/wiki/Q21984423)  
**Source**: https://4ort.xyz/entity/mitogen-activated-protein-kinase-kinase-1-q21984423


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P31938)
3. Q20641742
4. [Sensitive detection of idiotypic platelet-reactive alloantibodies by an electrical protein chip](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938)
6. [Small GTPase RBJ mediates nuclear entrapment of MEK1/MEK2 in tumor progression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938)
7. [Active Mek2 as a regulatory scaffold that promotes Pin1 binding to BPGAP1 to suppress BPGAP1-induced acute Erk activation and cell migration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938)
8. [JSAP1, a novel jun N-terminal protein kinase (JNK)-binding protein that functions as a Scaffold factor in the JNK signaling pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938)
9. [The ERK signaling cascade--views from different subcellular compartments](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938)
10. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P31938&geneProductId=UniProtKB:P31938)
11. [Role of the nude gene in epithelial terminal differentiation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P31938&geneProductId=UniProtKB:P31938)
12. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938)
13. [Role of the nude gene in epithelial terminal differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938)
14. [Phosphoinositide 3-kinase-dependent inhibition of dendritic cell interleukin-12 production by Giardia lamblia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938)
15. [The protein phosphatase 2A regulatory subunits B'beta and B'delta mediate sustained TrkA neurotrophin receptor autophosphorylation and neuronal differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938)
16. [B-RAF kinase drives developmental axon growth and promotes axon regeneration in the injured mature CNS](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938)
17. [Mouse and human phenotypes indicate a critical conserved role for ERK2 signaling in neural crest development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938)
18. [Shp2-dependent ERK signaling is essential for induction of Bergmann glia and foliation of the cerebellum](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938)
19. [Embryonic death of Mek1-deficient mice reveals a role for this kinase in angiogenesis in the labyrinthine region of the placenta](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938)
20. [The Grb2/Mek pathway represses Nanog in murine embryonic stem cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938)
21. [Crucial requirement of ERK/MAPK signaling in respiratory tract development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938)
22. [Presenilin acts as a positive regulator of basal level activity of ERK through the Raf-MEK1 signaling pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938)
23. [EphA receptors direct the differentiation of mammalian neural precursor cells through a mitogen-activated protein kinase-dependent pathway](http://www.ebi.ac.uk/QuickGO/annotations?protein=P31938&geneProductId=UniProtKB:P31938)
24. [EphA receptors direct the differentiation of mammalian neural precursor cells through a mitogen-activated protein kinase-dependent pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31938)
25. ensembl Release 106