# Mitogen-activated protein kinase 3

> mammalian protein found in Mus musculus

**Wikidata**: [Q15328869](https://www.wikidata.org/wiki/Q15328869)  
**Source**: https://4ort.xyz/entity/mitogen-activated-protein-kinase-3-q15328869


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q63844)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63844)
5. [p53-dependent inhibition of FKHRL1 in response to DNA damage through protein kinase SGK1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63844)
6. [Phosphorylation-dependent paxillin-ERK association mediates hepatocyte growth factor-stimulated epithelial morphogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63844)
7. [Erk MAP kinase regulates branching morphogenesis in the developing mouse kidney](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63844&geneProductId=UniProtKB:Q63844)
8. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63844&geneProductId=UniProtKB:Q63844)
9. [Role of the nude gene in epithelial terminal differentiation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63844&geneProductId=UniProtKB:Q63844)
10. [MUC20 suppresses the hepatocyte growth factor-induced Grb2-Ras pathway by binding to a multifunctional docking site of met](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63844&geneProductId=UniProtKB:Q63844)
11. [Treatment of cells with the angiogenic inhibitor fumagillin results in increased stability of eukaryotic initiation factor 2-associated glycoprotein, p67, and reduced phosphorylation of extracellular signal-regulated kinases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63844)
12. [Vanishin is a novel ubiquitinylated death-effector domain protein that blocks ERK activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63844)
13. [ERK1 and ERK2 regulate embryonic stem cell self-renewal through phosphorylation of Klf4.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63844)
14. [Regulation of neuronal pH by the metabotropic Zn2+‐sensing Gq‐coupled receptor, mZnR/GPR39](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63844)
15. [Erk MAP kinase regulates branching morphogenesis in the developing mouse kidney](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63844)
16. [Role of the nude gene in epithelial terminal differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63844)
17. [MUC20 suppresses the hepatocyte growth factor-induced Grb2-Ras pathway by binding to a multifunctional docking site of met](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63844)
18. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63844)
19. [The ERK signaling cascade--views from different subcellular compartments](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63844)
20. [A beta-arrestin-dependent scaffold is associated with prolonged MAPK activation in pseudopodia during protease-activated receptor-2-induced chemotaxis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63844)
21. [The ERK signaling cascade--views from different subcellular compartments](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63844&geneProductId=UniProtKB:Q63844)
22. [Prolonged Nuclear Retention of Activated Extracellular Signal-regulated Protein Kinase Promotes Cell Death Generated by Oxidative Toxicity or Proteasome Inhibition in a Neuronal Cell Line](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63844&geneProductId=UniProtKB:Q63844)
23. [Pecam-1 is a modulator of stat family member phosphorylation and localization: lessons from a transgenic mouse](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63844&geneProductId=UniProtKB:Q63844)
24. [Copper/zinc superoxide dismutase attenuates neuronal cell death by preventing extracellular signal-regulated kinase activation after transient focal cerebral ischemia in mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63844&geneProductId=UniProtKB:Q63844)
25. [Siglec-15 Protein Regulates Formation of Functional Osteoclasts in Concert with DNAX-activating Protein of 12 kDa (DAP12)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63844)
26. [Pecam-1 is a modulator of stat family member phosphorylation and localization: lessons from a transgenic mouse](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63844)
27. [Prolonged Nuclear Retention of Activated Extracellular Signal-regulated Protein Kinase Promotes Cell Death Generated by Oxidative Toxicity or Proteasome Inhibition in a Neuronal Cell Line](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63844)
28. [Copper/zinc superoxide dismutase attenuates neuronal cell death by preventing extracellular signal-regulated kinase activation after transient focal cerebral ischemia in mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63844)
29. [Crucial requirement of ERK/MAPK signaling in respiratory tract development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63844)
30. [Mouse and human phenotypes indicate a critical conserved role for ERK2 signaling in neural crest development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63844)
31. [Identification of Lps2 as a key transducer of MyD88-independent TIR signalling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63844)
32. [Inhibition of ERK1/2 and activation of liver X receptor synergistically induce macrophage ABCA1 expression and cholesterol efflux](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63844)
33. [TLR2 and RIP2 pathways mediate autophagy of Listeria monocytogenes via extracellular signal-regulated kinase (ERK) activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63844)
34. [ERK phosphorylation potentiates Elk-1-mediated ternary complex formation and transactivation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63844)
35. [Cytokine-like 1 (Cytl1) regulates the chondrogenesis of mesenchymal cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63844)
36. [Shp2-dependent ERK signaling is essential for induction of Bergmann glia and foliation of the cerebellum](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63844)
37. [Metabotropic glutamate receptor subtypes 1 and 5 are activators of extracellular signal-regulated kinase signaling required for inflammatory pain in mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63844)
38. [Gain-of-function mutation in FGFR3 in mice leads to decreased bone mass by affecting both osteoblastogenesis and osteoclastogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63844)
39. [Human lysyl-tRNA synthetase is secreted to trigger proinflammatory response](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63844)
40. [Phosphoinositide 3-kinase-dependent inhibition of dendritic cell interleukin-12 production by Giardia lamblia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63844)
41. [MicroRNA-494, Upregulated by Tumor Necrosis Factor-α, Desensitizes Insulin Effect in C2C12 Muscle Cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63844)
42. ensembl Release 106