# mitogen-activated protein kinase 14

> mammalian protein found in Homo sapiens

**Wikidata**: [Q6714402](https://www.wikidata.org/wiki/Q6714402)  
**Source**: https://4ort.xyz/entity/mitogen-activated-protein-kinase-14-q6714402


## References

1. UniProt
2. IUPHAR/BPS Guide to PHARMACOLOGY
3. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL1088750)
4. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL2031465)
5. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL1230065)
6. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL2103838)
7. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL103667)
8. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL1938400)
9. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL1088751)
10. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL2364626)
11. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL514201)
12. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL1090090)
13. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL119385)
14. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL1090173)
15. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL203567)
16. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q16539)
17. Q20641742
18. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16539)
19. [LZAP inhibits p38 MAPK (p38) phosphorylation and activity by facilitating p38 association with the wild-type p53 induced phosphatase 1 (WIP1)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16539)
20. [Molecular cloning and characterization of a novel dual specificity phosphatase, MKP-5](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16539)
21. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16539&geneProductId=UniProtKB:Q16539)
22. [DNA Damage Activates a Spatially Distinct Late Cytoplasmic Cell-Cycle Checkpoint Network Controlled by MK2-Mediated RNA Stabilization](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16539&geneProductId=UniProtKB:Q16539)
23. [Targeting of p38 mitogen-activated protein kinases to MEF2 transcription factors](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16539&geneProductId=UniProtKB:Q16539)
24. [A protein kinase involved in the regulation of inflammatory cytokine biosynthesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16539&geneProductId=UniProtKB:Q16539)
25. [Protein Arginine Methyltransferase 1 Interacts with and Activates p38α to Facilitate Erythroid Differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16539)
26. [p38 and a p38-interacting protein are critical for downregulation of E-cadherin during mouse gastrulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16539)
27. [Interactome mapping of the phosphatidylinositol 3-kinase-mammalian target of rapamycin pathway identifies deformed epidermal autoregulatory factor-1 as a new glycogen synthase kinase-3 interactor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16539)
28. [Protein interaction data set highlighted with human Ras-MAPK/PI3K signaling pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16539)
29. [A human interactome in three quantitative dimensions organized by stoichiometries and abundances](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16539)
30. [p38 phosphorylates Rb on Ser567 by a novel, cell cycle-independent mechanism that triggers Rb-Hdm2 interaction and apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16539)
31. [Towards a proteome-scale map of the human protein–protein interaction network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16539)
32. [DUSP26 negatively affects the proliferation of epithelial cells, an effect not mediated by dephosphorylation of MAPKs](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16539)
33. [Metal-dependent protein phosphatase 1A functions as an extracellular signal-regulated kinase phosphatase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16539)
34. [A human MAP kinase interactome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16539)
35. [A new p38 MAP kinase-regulated transcriptional coactivator that stimulates p53-dependent apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16539)
36. [Mxi2 promotes stimulus-independent ERK nuclear translocation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16539)
37. [Stress-induced inhibition of ERK1 and ERK2 by direct interaction with p38 MAP kinase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16539)
38. [RSK-B, a Novel Ribosomal S6 Kinase Family Member, Is a CREB Kinase under Dominant Control of p38α Mitogen-activated Protein Kinase (p38αMAPK)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16539)
39. [ETS-dependent p16INK4a and p21waf1/cip1 gene expression upon endothelin-1 stimulation in malignant versus and non-malignant proximal tubule cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16539)
40. [Analysis of protein-protein interactions in cross-talk pathways reveals CRKL protein as a novel prognostic marker in hepatocellular carcinoma](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16539)
41. [Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16539)
42. [Phosphorylation of the kinase interaction motif in mitogen-activated protein (MAP) kinase phosphatase-4 mediates cross-talk between protein kinase A and MAP kinase signaling pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16539)
43. [The protein interaction landscape of the human CMGC kinase group](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16539)
44. [A directed protein interaction network for investigating intracellular signal transduction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16539)
45. [Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16539)
46. [Using an in Situ Proximity Ligation Assay to Systematically Profile Endogenous Protein–Protein Interactions in a Pathway Network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16539)
47. [Phosphorylation of pRB at Ser612 by Chk1/2 leads to a complex between pRB and E2F-1 after DNA damage](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16539)
48. [Crystal structure of the p38 alpha-MAPKAP kinase 2 heterodimer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16539)
49. [A novel regulatory mechanism of MAP kinases activation and nuclear translocation mediated by PKA and the PTP-SL tyrosine phosphatase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16539)
50. [Toward an understanding of the protein interaction network of the human liver](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16539)