# Mitogen-activated protein kinase 1

> mammalian protein found in Mus musculus

**Wikidata**: [Q15317763](https://www.wikidata.org/wiki/Q15317763)  
**Source**: https://4ort.xyz/entity/mitogen-activated-protein-kinase-1-q15317763


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P63085)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P63085)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63085)
6. [Gab1 is an integrator of cell death versus cell survival signals in oxidative stress](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63085)
7. [MAP kinase phosphatase 3 (MKP3) interacts with and is phosphorylated by protein kinase CK2alpha](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63085)
8. [Suppression of mitochondrial respiration through recruitment of p160 myb binding protein to PGC-1alpha: modulation by p38 MAPK](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63085)
9. [Phosphorylation-dependent paxillin-ERK association mediates hepatocyte growth factor-stimulated epithelial morphogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63085)
10. [Molecular cloning of Ebitein1: a novel extracellular signal-regulated kinase 2-binding protein in testis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63085)
11. [Scaffold protein Dlgh1 coordinates alternative p38 kinase activation, directing T cell receptor signals toward NFAT but not NF-kappaB transcription factors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63085)
12. [Treatment of cells with the angiogenic inhibitor fumagillin results in increased stability of eukaryotic initiation factor 2-associated glycoprotein, p67, and reduced phosphorylation of extracellular signal-regulated kinases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63085)
13. [The forkhead genes, Foxc1 and Foxc2, regulate paraxial versus intermediate mesoderm cell fate](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63085)
14. [ERK2 shows a restrictive and locally selective mechanism of recognition by its tyrosine phosphatase inactivators not shared by its activator MEK1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63085)
15. [Interaction of mitogen-activated protein kinases with the kinase interaction motif of the tyrosine phosphatase PTP-SL provides substrate specificity and retains ERK2 in the cytoplasm](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63085)
16. [Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63085)
17. [Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63085)
18. [The collagen receptor discoidin domain receptor 2 stabilizes SNAIL1 to facilitate breast cancer metastasis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63085)
19. [Identification of Novel Host Interactors of Effectors Secreted by Salmonella and Citrobacter.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63085)
20. [Pseudorabies virus tegument protein Us2 recruits the mitogen-activated protein kinase extracellular-regulated kinase (ERK) to membranes through interaction with the ERK common docking domain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63085)
21. [Bioinformatics and cellular signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63085)
22. [Targeted tandem affinity purification of PSD-95 recovers core postsynaptic complexes and schizophrenia susceptibility proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63085)
23. [A Novel RNA Polymerase II C-terminal Domain Phosphatase That Preferentially Dephosphorylates Serine 5](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63085)
24. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63085&geneProductId=UniProtKB:P63085)
25. [Activation of p42 mitogen-activated protein kinase (MAPK), but not c-Jun NH(2)-terminal kinase, induces phosphorylation and stabilization of MAPK phosphatase XCL100 in Xenopus oocytes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63085&geneProductId=UniProtKB:P63085)
26. [Role of the nude gene in epithelial terminal differentiation](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P63085)
27. [ERK is a novel regulatory kinase for poly(A) polymerase](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P63085)
28. [The Motheaten Mutation Rescues B Cell Signaling and Development in CD45-deficient Mice](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P63085)
29. [MUC20 suppresses the hepatocyte growth factor-induced Grb2-Ras pathway by binding to a multifunctional docking site of met](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P63085)
30. [Reconstitution of B cell antigen receptor-induced signaling events in a nonlymphoid cell line by expressing the Syk protein-tyrosine kinase](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P63085)
31. [Copper/zinc superoxide dismutase attenuates neuronal cell death by preventing extracellular signal-regulated kinase activation after transient focal cerebral ischemia in mice](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P63085)
32. [Presenilin acts as a positive regulator of basal level activity of ERK through the Raf-MEK1 signaling pathway](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P63085)
33. [Signaling capacity of the T cell antigen receptor is negatively regulated by the PTP1C tyrosine phosphatase](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P63085)
34. [Small Molecule Inhibition of ERK Dimerization Prevents Tumorigenesis by RAS-ERK Pathway Oncogenes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63085)
35. [Role of the nude gene in epithelial terminal differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63085)
36. [ERK is a novel regulatory kinase for poly(A) polymerase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63085)
37. [Copper/zinc superoxide dismutase attenuates neuronal cell death by preventing extracellular signal-regulated kinase activation after transient focal cerebral ischemia in mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63085)
38. [The Motheaten Mutation Rescues B Cell Signaling and Development in CD45-deficient Mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63085)
39. [Signaling capacity of the T cell antigen receptor is negatively regulated by the PTP1C tyrosine phosphatase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63085)
40. [MUC20 suppresses the hepatocyte growth factor-induced Grb2-Ras pathway by binding to a multifunctional docking site of met](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63085)
41. [Presenilin acts as a positive regulator of basal level activity of ERK through the Raf-MEK1 signaling pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63085)
42. [Reconstitution of B cell antigen receptor-induced signaling events in a nonlymphoid cell line by expressing the Syk protein-tyrosine kinase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63085)
43. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63085)
44. [Regulation of neuronal pH by the metabotropic Zn2+‐sensing Gq‐coupled receptor, mZnR/GPR39](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63085)
45. [MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63085)
46. [Activation of p42 mitogen-activated protein kinase (MAPK), but not c-Jun NH(2)-terminal kinase, induces phosphorylation and stabilization of MAPK phosphatase XCL100 in Xenopus oocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63085)
47. [Prolonged Nuclear Retention of Activated Extracellular Signal-regulated Protein Kinase Promotes Cell Death Generated by Oxidative Toxicity or Proteasome Inhibition in a Neuronal Cell Line](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63085&geneProductId=UniProtKB:P63085)
48. [Spatial and temporal patterns of ERK signaling during mouse embryogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63085&geneProductId=UniProtKB:P63085)
49. [Copper/zinc superoxide dismutase attenuates neuronal cell death by preventing extracellular signal-regulated kinase activation after transient focal cerebral ischemia in mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63085&geneProductId=UniProtKB:P63085)
50. [Pseudorabies virus tegument protein Us2 recruits the mitogen-activated protein kinase extracellular-regulated kinase (ERK) to membranes through interaction with the ERK common docking domain](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63085&geneProductId=UniProtKB:P63085)