# Minimizing Patient Burden Through the Use of Historical Subject-Level Data in Innovative Confirmatory Clinical Trials: Review of Methods and Opportunities

> Research article (Therapeutic Innovation & Regulatory Science, 2018) · cited 117× · AI/ML

**Wikidata**: [openalex:W2809368684](https://www.wikidata.org/wiki/openalex:W2809368684)  
**Source**: https://4ort.xyz/entity/minimizing-patient-burden-through-the-use-of-historical-subject-level-data-in-innovative-confirmatory-clinical-trials-re