# Midline 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21132775](https://www.wikidata.org/wiki/Q21132775)  
**Source**: https://4ort.xyz/entity/midline-1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O15344)
3. Q20641742
4. [MID1 and MID2 homo- and heterodimerise to tether the rapamycin-sensitive PP2A regulatory subunit, alpha 4, to microtubules: implications for the clinical variability of X-linked Opitz GBBB syndrome and other developmental disorders](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15344)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15344)
6. [A human interactome in three quantitative dimensions organized by stoichiometries and abundances](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15344)
7. [Next-generation sequencing to generate interactome datasets](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15344)
8. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15344)
9. [Widespread macromolecular interaction perturbations in human genetic disorders](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15344)
10. [Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15344)
11. [TRIM27 negatively regulates NOD2 by ubiquitination and proteasomal degradation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15344)
12. [Systematic Analysis of Dimeric E3-RING Interactions Reveals Increased Combinatorial Complexity in Human Ubiquitination Networks](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15344)
13. [Cytokine activation of p38 mitogen-activated protein kinase and apoptosis is opposed by alpha-4 targeting of protein phosphatase 2A for site-specific dephosphorylation of MEK3.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15344)
14. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O15344&geneProductId=UniProtKB:O15344)
15. [The Opitz syndrome gene product, MID1, associates with microtubules](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15344)
16. [Active transport of the ubiquitin ligase MID1 along the microtubules is regulated by protein phosphatase 2A](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15344)
17. [Opitz G/BBB syndrome, a defect of midline development, is due to mutations in a new RING finger gene on Xp22](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15344)
18. Ensembl Release 99
19. The MID1 gene product in physiology and disease