# Methyltransferase like 3

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21124024](https://www.wikidata.org/wiki/Q21124024)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/METTL3)  
**Source**: https://4ort.xyz/entity/methyltransferase-like-3


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q86U44)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86U44)
5. [N6-methyladenosine marks primary microRNAs for processing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86U44)
6. [Interactions, localization and phosphorylation of the m6A generating METTL3-METTL14-WTAP complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86U44)
7. [m(6)A RNA methylation promotes XIST-mediated transcriptional repression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86U44)
8. [SUMOylation of the m6A-RNA methyltransferase METTL3 modulates its function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86U44)
9. [RNA m6A methylation regulates the ultraviolet-induced DNA damage response.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86U44&geneProductId=UniProtKB:Q86U44)
10. [Purification and cDNA cloning of the AdoMet-binding subunit of the human mRNA (N6-adenosine)-methyltransferase](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86U44&geneProductId=UniProtKB:Q86U44)
11. [Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86U44&geneProductId=UniProtKB:Q86U44)
12. [N6-methyladenosine-dependent regulation of messenger RNA stability](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86U44&geneProductId=UniProtKB:Q86U44)
13. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86U44&geneProductId=UniProtKB:Q86U44)
14. [A METTL3-METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86U44&geneProductId=UniProtKB:Q86U44)
15. [Structural basis of N(6)-adenosine methylation by the METTL3-METTL14 complex](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86U44&geneProductId=UniProtKB:Q86U44)
16. [Structural Basis for Cooperative Function of Mettl3 and Mettl14 Methyltransferases](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86U44&geneProductId=UniProtKB:Q86U44)
17. [Structural insights into the molecular mechanism of the m(6)A writer complex](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86U44&geneProductId=UniProtKB:Q86U44)
18. [Structural basis of N(6)-adenosine methylation by the METTL3-METTL14 complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86U44)
19. [Structural Basis for Cooperative Function of Mettl3 and Mettl14 Methyltransferases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86U44)
20. [VIRMA mediates preferential m6A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86U44)
21. [A human interactome in three quantitative dimensions organized by stoichiometries and abundances](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86U44)
22. [N6-methyladenosine modification destabilizes developmental regulators in embryonic stem cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86U44)
23. [A METTL3-METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86U44)
24. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86U44&geneProductId=UniProtKB:Q86U44)
25. [Purification and cDNA cloning of the AdoMet-binding subunit of the human mRNA (N6-adenosine)-methyltransferase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86U44)
26. [Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86U44)
27. [RNA m6A methylation regulates the ultraviolet-induced DNA damage response.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86U44)
28. [N6-methyladenosine-dependent regulation of messenger RNA stability](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86U44)
29. [Structural insights into the molecular mechanism of the m(6)A writer complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86U44)
30. [m(6)A RNA methylation promotes XIST-mediated transcriptional repression](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86U44&geneProductId=UniProtKB:Q86U44)
31. [VIRMA mediates preferential m6A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86U44&geneProductId=UniProtKB:Q86U44)
32. [SUMOylation of the m6A-RNA methyltransferase METTL3 modulates its function](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86U44&geneProductId=UniProtKB:Q86U44)
33. [Interactions, localization and phosphorylation of the m6A generating METTL3-METTL14-WTAP complex](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86U44&geneProductId=UniProtKB:Q86U44)
34. [Perturbation of m6A writers reveals two distinct classes of mRNA methylation at internal and 5' sites](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86U44&geneProductId=UniProtKB:Q86U44)
35. [Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86U44&geneProductId=UniProtKB:Q86U44)
36. [Dynamic m(6)A mRNA methylation directs translational control of heat shock response](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86U44&geneProductId=UniProtKB:Q86U44)
37. [Dynamic m(6)A mRNA methylation directs translational control of heat shock response](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86U44)
38. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86U44)
39. [Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86U44)
40. [Perturbation of m6A writers reveals two distinct classes of mRNA methylation at internal and 5' sites](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86U44)
41. [5' UTR m(6)A Promotes Cap-Independent Translation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86U44)
42. [N(6)-methyladenosine-dependent RNA structural switches regulate RNA-protein interactions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86U44)
43. [N(6)-methyladenosine-dependent RNA structural switches regulate RNA-protein interactions](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86U44&geneProductId=UniProtKB:Q86U44)
44. [HNRNPA2B1 Is a Mediator of m(6)A-Dependent Nuclear RNA Processing Events](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86U44&geneProductId=UniProtKB:Q86U44)
45. [HNRNPA2B1 Is a Mediator of m(6)A-Dependent Nuclear RNA Processing Events](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86U44)
46. Ensembl Release 99