# methylenetetrahydrofolate reductase

> mammalian protein found in Homo sapiens

**Wikidata**: [Q424709](https://www.wikidata.org/wiki/Q424709)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/Methylenetetrahydrofolate_reductase)  
**Source**: https://4ort.xyz/entity/methylenetetrahydrofolate-reductase


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P42898)
3. Q20641742
4. Freebase Data Dumps. 2013
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42898&geneProductId=UniProtKB:P42898)
6. [Characterization of mutations in severe methylenetetrahydrofolate reductase deficiency reveals an FAD-responsive mutation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42898&geneProductId=UniProtKB:P42898)
7. [A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42898&geneProductId=UniProtKB:P42898)
8. [Insights into severe 5,10-methylenetetrahydrofolate reductase deficiency: molecular genetic and enzymatic characterization of 76 patients](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42898&geneProductId=UniProtKB:P42898)
9. [Functional characterization of human methylenetetrahydrofolate reductase in Saccharomyces cerevisiae](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42898&geneProductId=UniProtKB:P42898)
10. [MTHFR promotes heterochromatin maintenance](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42898&geneProductId=UniProtKB:P42898)
11. [Novel associations of CPS1, MUT, NOX4, and DPEP1 with plasma homocysteine in a healthy population: a genome-wide evaluation of 13 974 participants in the Women's Genome Health Study](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42898&geneProductId=UniProtKB:P42898)
12. Ensembl Release 99
13. Identifiers.org
14. UMLS 2023
15. [OpenAlex](https://docs.openalex.org/download-snapshot/snapshot-data-format)