# Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21120060](https://www.wikidata.org/wiki/Q21120060)  
**Source**: https://4ort.xyz/entity/methylenetetrahydrofolate-dehydrogenase-nadp-dependent-2-methenyltetrahydrofolate-cyclohydrolase-q21120060


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P13995)
3. Q20641742
4. [Swiss-Prot](http://www.uniprot.org/uniprot/P13995.txt?version=168)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13995)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P13995&geneProductId=UniProtKB:P13995)
7. [NAD-dependent methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase is the mammalian homolog of the mitochondrial enzyme encoded by the yeast MIS1 gene](http://www.ebi.ac.uk/QuickGO/annotations?protein=P13995&geneProductId=UniProtKB:P13995)
8. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=P13995&geneProductId=UniProtKB:P13995)
9. [Magnesium and phosphate ions enable NAD binding to methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13995)
10. [NAD-dependent methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase is the mammalian homolog of the mitochondrial enzyme encoded by the yeast MIS1 gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13995)
11. [Magnesium and phosphate ions enable NAD binding to methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase](http://www.ebi.ac.uk/QuickGO/annotations?protein=P13995&geneProductId=UniProtKB:P13995)
12. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13995)
13. [Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach](http://www.ebi.ac.uk/QuickGO/annotations?protein=P13995&geneProductId=UniProtKB:P13995)
14. [Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13995)
15. Ensembl Release 99