Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
type: Thing
description: mammalian protein found in Rattus norvegicus
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P352
  value: B2GUZ3
additional property: PropertyValue
  property ID: P361
  value: formate-tetrahydrofolate ligase
additional property: PropertyValue
  property ID: P361
  value: NAD(P)-binding domain superfamily
additional property: PropertyValue
  property ID: P361
  value: Tetrahydrofolate dehydrogenase/cyclohydrolase
additional property: PropertyValue
  property ID: P527
  value: Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain
additional property: PropertyValue
  property ID: P527
  value: Formate-tetrahydrofolate ligase, FTHFS, conserved site
additional property: PropertyValue
  property ID: P527
  value: Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
additional property: PropertyValue
  property ID: P637
  value: NP_001101932
additional property: PropertyValue
  property ID: P637
  value: XP_038937152
additional property: PropertyValue
  property ID: P680
  value: formate-tetrahydrofolate ligase activity
additional property: PropertyValue
  property ID: P680
  value: methenyltetrahydrofolate cyclohydrolase activity
additional property: PropertyValue
  property ID: P680
  value: methylenetetrahydrofolate dehydrogenase (NADP+) activity
additional property: PropertyValue
  property ID: P681
  value: cytoplasm
additional property: PropertyValue
  property ID: P681
  value: mitochondrion
additional property: PropertyValue
  property ID: P681
  value: cellular component
additional property: PropertyValue
  property ID: P682
  value: neural tube closure
additional property: PropertyValue
  property ID: P682
  value: purine nucleobase biosynthetic process
additional property: PropertyValue
  property ID: P682
  value: 10-formyltetrahydrofolate biosynthetic process
additional property: PropertyValue
  property ID: P702
  value: Mthfd1l
additional property: PropertyValue
  property ID: P703
  value: brown rat
additional property: PropertyValue
  property ID: P705
  value: ENSRNOP00000026564
confidence:
  popularity graph score:
    score: 0.001
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 7
      unique citations norm: 0.003
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 7
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: B2GUZ3
    source count: 1
    confidence: 0.2
  P361:
    value: Q24776360
    source count: 1
    confidence: 0.2
    value label: formate-tetrahydrofolate ligase
  P361:
    value: Q41797412
    source count: 1
    confidence: 0.2
    value label: NAD(P)-binding domain superfamily
  P361:
    value: Q24784799
    source count: 1
    confidence: 0.2
    value label: Tetrahydrofolate dehydrogenase/cyclohydrolase
  P361:
    value: Q24726930
    source count: 1
    confidence: 0.2
    value label: P-loop containing nucleoside triphosphate hydrolase
  P361:
    value: Q83137500
    source count: 1
    confidence: 0.2
    value label: Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain, protein family
  P527:
    value: Q24742125
    source count: 1
    confidence: 0.2
    value label: Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain
  P527:
    value: Q24777026
    source count: 1
    confidence: 0.2
    value label: Formate-tetrahydrofolate ligase, FTHFS, conserved site
  P527:
    value: Q24774915
    source count: 1
    confidence: 0.2
    value label: Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
  P637:
    value: NP_001101932
    source count: 1
    confidence: 0.2
  P637:
    value: XP_038937152
    source count: 1
    confidence: 0.2
  P680:
    value: Q21111746
    source count: 2
    confidence: 0.4
    value label: formate-tetrahydrofolate ligase activity
  P680:
    value: Q21111747
    source count: 1
    confidence: 0.2
    value label: methenyltetrahydrofolate cyclohydrolase activity
  P680:
    value: Q21111750
    source count: 2
    confidence: 0.4
    value label: methylenetetrahydrofolate dehydrogenase (NADP+) activity
  P680:
    value: Q14817981
    source count: 1
    confidence: 0.2
    value label: ATP binding
  P680:
    value: Q14860489
    source count: 1
    confidence: 0.2
    value label: molecular function
  P681:
    value: Q79899
    source count: 1
    confidence: 0.2
    value label: cytoplasm
  P681:
    value: Q39572
    source count: 1
    confidence: 0.2
    value label: mitochondrion
  P681:
    value: Q5058355
    source count: 1
    confidence: 0.2
    value label: cellular component
  P681:
    value: Q39572
    source count: 2
    confidence: 0.4
    value label: mitochondrion
  P682:
    value: Q14885826
    source count: 1
    confidence: 0.2
    value label: neural tube closure
  P682:
    value: Q14914076
    source count: 1
    confidence: 0.2
    value label: purine nucleobase biosynthetic process
  P682:
    value: Q21111752
    source count: 1
    confidence: 0.2
    value label: 10-formyltetrahydrofolate biosynthetic process

value: Q14897664
source count: 1
confidence: 0.2
value label: embryonic neurocranium morphogenesis

value: Q14897665
source count: 1
confidence: 0.2
value label: embryonic viscerocranium morphogenesis

value: Q24395840
source count: 1
confidence: 0.2
value label: Mthfd1l

value: Q184224
source count: 1
confidence: 0.2
value label: brown rat

value: ENSRNOP00000026564
source count: 1
confidence: 0.2

source: GOA
stated in qid: Q28018111
retrieved: 2019-02-14

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2019-02-14

source: GOA
stated in qid: Q28018111
retrieved: 2017-09-16

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2022-05-25

source: Q20641742
stated in qid: Q20641742
retrieved: 2022-03-20

source: ensembl Release 106
stated in qid: Q111699881

wikidata id: Q29524788
domain: protein
level: standard
html url: https://4ort.xyz/entity/methylenetetrahydrofolate-dehydrogenase-nadp-dependent-1-like-q29524788
markdown url: https://4ort.xyz/entity/methylenetetrahydrofolate-dehydrogenase-nadp-dependent-1-like-q29524788.md
facts url summary: https://4ort.xyz/entity/methylenetetrahydrofolate-dehydrogenase-nadp-dependent-1-like-q29524788/facts.json
facts url standard: https://4ort.xyz/entity/methylenetetrahydrofolate-dehydrogenase-nadp-dependent-1-like-q29524788/facts.json
facts url full: https://4ort.xyz/entity/methylenetetrahydrofolate-dehydrogenase-nadp-dependent-1-like-q29524788/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-04T14:51:06.571947Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T14:58:52.713056+00:00Z