# Methyl CpG binding protein 2

> mammalian protein found in Mus musculus

**Wikidata**: [Q21499136](https://www.wikidata.org/wiki/Q21499136)  
**Source**: https://4ort.xyz/entity/methyl-cpg-binding-protein-2


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q9Z2D6)
3. Q20641742
4. [Enhanced anxiety and stress-induced corticosterone release are associated with increased Crh expression in a mouse model of Rett syndrome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2D6)
5. [Loss of silent-chromatin looping and impaired imprinting of DLX5 in Rett syndrome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2D6)
6. [MeCP2, a key contributor to neurological disease, activates and represses transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2D6)
7. [Gene expression analysis exposes mitochondrial abnormalities in a mouse model of Rett syndrome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2D6)
8. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z2D6&geneProductId=UniProtKB:Q9Z2D6)
9. [Loss of silent-chromatin looping and impaired imprinting of DLX5 in Rett syndrome](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z2D6&geneProductId=UniProtKB:Q9Z2D6)
10. [MeCP2, a key contributor to neurological disease, activates and represses transcription](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z2D6&geneProductId=UniProtKB:Q9Z2D6)
11. [Gene expression analysis exposes mitochondrial abnormalities in a mouse model of Rett syndrome](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z2D6&geneProductId=UniProtKB:Q9Z2D6)
12. [DNA Methylation-Related Chromatin Remodeling in Activity-Dependent Bdnf Gene Regulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2D6)
13. [Rett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2D6)
14. [Structure of the MeCP2-TBLR1 complex reveals a molecular basis for Rett syndrome and related disorders](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2D6)
15. [Interaction between chromatin proteins MECP2 and ATRX is disrupted by mutations that cause inherited mental retardation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2D6)
16. [Brahma links the SWI/SNF chromatin-remodeling complex with MeCP2-dependent transcriptional silencing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2D6)
17. [ATRX partners with cohesin and MeCP2 and contributes to developmental silencing of imprinted genes in the brain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2D6)
18. [A novel role for cardiac ankyrin repeat protein Ankrd1/CARP as a co-activator of the p53 tumor suppressor protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2D6)
19. [Components of the DNA methylation system of chromatin control are RNA-binding proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2D6)
20. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2D6)
21. [MicroRNA-22 Regulates Smooth Muscle Cell Differentiation From Stem Cells by Targeting Methyl CpG–Binding Protein 2](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z2D6&geneProductId=UniProtKB:Q9Z2D6)
22. [MicroRNA-22 Regulates Smooth Muscle Cell Differentiation From Stem Cells by Targeting Methyl CpG–Binding Protein 2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2D6)
23. [Analysis of protein domains and Rett syndrome mutations indicate that multiple regions influence chromatin-binding dynamics of the chromatin-associated protein MECP2 in vivo](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z2D6&geneProductId=UniProtKB:Q9Z2D6)
24. [Components of the DNA methylation system of chromatin control are RNA-binding proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z2D6&geneProductId=UniProtKB:Q9Z2D6)
25. [Enhanced anxiety and stress-induced corticosterone release are associated with increased Crh expression in a mouse model of Rett syndrome](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z2D6&geneProductId=UniProtKB:Q9Z2D6)
26. [Interaction between chromatin proteins MECP2 and ATRX is disrupted by mutations that cause inherited mental retardation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z2D6&geneProductId=UniProtKB:Q9Z2D6)
27. [MeCP2 deficiency in Rett syndrome causes epigenetic aberrations at the PWS/AS imprinting center that affects UBE3A expression](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z2D6&geneProductId=UniProtKB:Q9Z2D6)
28. [DNA Methylation-Related Chromatin Remodeling in Activity-Dependent Bdnf Gene Regulation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z2D6&geneProductId=UniProtKB:Q9Z2D6)
29. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2D6)
30. [MeCP2 deficiency in Rett syndrome causes epigenetic aberrations at the PWS/AS imprinting center that affects UBE3A expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2D6)
31. [Dynamic changes in the localization of five members of the methyl binding domain (MBD) gene family during murine and bovine preimplantation embryo development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2D6)
32. [Analysis of mammalian proteins involved in chromatin modification reveals new metaphase centromeric proteins and distinct chromosomal distribution patterns](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z2D6&geneProductId=UniProtKB:Q9Z2D6)
33. [Insight into Rett syndrome: MeCP2 levels display tissue- and cell-specific differences and correlate with neuronal maturation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z2D6&geneProductId=UniProtKB:Q9Z2D6)
34. [The major form of MeCP2 has a novel N-terminus generated by alternative splicing](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z2D6&geneProductId=UniProtKB:Q9Z2D6)
35. [Postnatal loss of methyl-CpG binding protein 2 in the forebrain is sufficient to mediate behavioral aspects of Rett syndrome in mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z2D6&geneProductId=UniProtKB:Q9Z2D6)
36. [Enhanced cell death in MeCP2 null cerebellar granule neurons exposed to excitotoxicity and hypoxia](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z2D6&geneProductId=UniProtKB:Q9Z2D6)
37. [A transcriptional repressor MeCP2 causing Rett syndrome is expressed in embryonic non-neuronal cells and controls their growth](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z2D6&geneProductId=UniProtKB:Q9Z2D6)
38. [Dynamic changes in the localization of five members of the methyl binding domain (MBD) gene family during murine and bovine preimplantation embryo development](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z2D6&geneProductId=UniProtKB:Q9Z2D6)
39. [Analysis of mammalian proteins involved in chromatin modification reveals new metaphase centromeric proteins and distinct chromosomal distribution patterns](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2D6)
40. [Insight into Rett syndrome: MeCP2 levels display tissue- and cell-specific differences and correlate with neuronal maturation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2D6)
41. [Postnatal loss of methyl-CpG binding protein 2 in the forebrain is sufficient to mediate behavioral aspects of Rett syndrome in mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2D6)
42. [Enhanced cell death in MeCP2 null cerebellar granule neurons exposed to excitotoxicity and hypoxia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2D6)
43. [A transcriptional repressor MeCP2 causing Rett syndrome is expressed in embryonic non-neuronal cells and controls their growth](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2D6)
44. [Learning and memory and synaptic plasticity are impaired in a mouse model of Rett syndrome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2D6)
45. [Dysregulation of brain-derived neurotrophic factor expression and neurosecretory function in Mecp2 null mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2D6)
46. [The transcriptional repressor Mecp2 regulates terminal neuronal differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2D6)
47. [A partial loss of function allele of methyl-CpG-binding protein 2 predicts a human neurodevelopmental syndrome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2D6)
48. [Hippocampal synaptic plasticity is impaired in the Mecp2-null mouse model of Rett syndrome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2D6)
49. [A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2D6)
50. [MeCP2 controls excitatory synaptic strength by regulating glutamatergic synapse number](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2D6)