# metabolomics

> scientific study of chemical processes involving metabolites

**Wikidata**: [Q12149006](https://www.wikidata.org/wiki/Q12149006)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/Metabolomics)  
**Source**: https://4ort.xyz/entity/metabolomics

## Summary
Metabolomics is the scientific study of chemical processes involving metabolites and the metabolome. It is an interdisciplinary branch of science and academic discipline that sits within omics and is closely connected to biochemistry and computational biology.

## Key Facts
- Metabolomics is defined as the scientific study of chemical processes involving metabolites and the metabolome.
- Instance of: branch of science, academic discipline, and interdisciplinary science.
- Subclass of: computational biology, biochemistry, and omics.
- Part of: medical biochemistry and metabolomics; proteomics and metabolomics.
- Common aliases include "metabolomic chemistry", "メタボローム解析", and "メタボロミックス".
- Sitelink count (Wikidata): 26.
- MeSH descriptor ID: D055432 (MeSH tree codes include H01.158.201.586 and H01.158.273.180.599).
- Freebase identifier: /m/03_pm1 (reference publication date 2013-10-28).
- GitHub topic tag: "metabolomics" (reference date 2022-05-16).

## FAQs
### Q: What does metabolomics study?
A: Metabolomics studies metabolites and the metabolome — the small-molecule chemical products of cellular and organismal processes. It focuses on the chemical processes involving those metabolites.

### Q: How is metabolomics related to other fields?
A: Metabolomics is a subclass of computational biology, biochemistry, and omics, and it is part of domains such as medical biochemistry and proteomics. It is interdisciplinary and uses data-analytical and modeling approaches from computational biology.

### Q: What are some specialized branches of metabolomics?
A: Named subfields include Exometabolomics, nmr-based metabolomics, soil metabolomics, and Stable Isotope Resolved Metabolomics (SIRM), which uses stable isotopes to trace metabolic pathways.

### Q: Where can I find a concise visual of metabolomics in systems biology?
A: A schematic associating systems-biology tools from genomics to metabolomics (showing the flow from DNA to phenotype and placing metabolomics at the phenotype-associated stage) is available among the provided image resources.

## Why It Matters
Metabolomics provides a direct chemical readout of the small molecules present in cells, tissues, organisms, and environments, linking biochemical activity to the phenotype. As an omics discipline and an interdisciplinary science, it complements genomics, transcriptomics, and proteomics by measuring the end products of biological processes. This makes metabolomics valuable for medical biochemistry and proteomics integration, for environmental and soil research (soil metabolomics), and for method development such as NMR-based approaches and isotope-tracing techniques (SIRM). Because metabolomics encompasses both experimental measurement and computational analysis, it bridges laboratory chemistry and data-driven computational biology. The field has recognized identifiers and resources (MeSH, Freebase, GitHub topic, encyclopedia entries) that support knowledge organization and reuse across biomedical, environmental, and computational domains.

## Notable For
- Being an interdisciplinary omics discipline that directly studies metabolites and the metabolome.
- Inclusion as a subclass of computational biology and biochemistry, emphasizing combined experimental and computational approaches.
- Having specialized subfields such as Exometabolomics, nmr-based metabolomics, soil metabolomics, and Stable Isotope Resolved Metabolomics (SIRM).
- Presence in curated biomedical and knowledge systems (MeSH D055432, Freebase /m/03_pm1, GitHub topic "metabolomics").
- Integration into resources and schematics that place metabolomics at the phenotype-associated stage of systems biology.

## Body

### Definition
- Metabolomics is the scientific study of chemical processes involving metabolites.
- It is concerned with the metabolome, the complete set of small-molecule chemicals in a biological system.

### Classification and Scope
- Instance of: branch of science, academic discipline, interdisciplinary science.
- Subclass of computational biology, biochemistry, and omics.
- Part of domains labeled "medical biochemistry and metabolomics" and "proteomics and metabolomics."

### Subfields and Related Areas
- Exometabolomics (class).
- nmr-based metabolomics (class).
- soil metabolomics (class) — research field studying metabolism in soil.
- Stable Isotope Resolved Metabolomics (SIRM) — specialized branch that employs stable isotopes to trace metabolic pathways.

### Methods and Approaches
- The field is associated with computational biology: it uses data-analytical and theoretical methods, mathematical modeling, and computational simulation techniques to study biological systems (as specified under the parent class computational biology).
- NMR-based methods are explicitly named as a class within metabolomics.

### Resources, Visuals, and Identifiers
- Images:
  - https://commons.wikimedia.org/wiki/Special:FilePath/SESI_and_metabolomics_research.png
  - https://commons.wikimedia.org/wiki/Special:FilePath/Metabolomic_analyses_(4071450997).jpg
  - Schematic linking systems-biology stages to metabolomics: https://commons.wikimedia.org/wiki/Special:FilePath/The_central_dogma_of_biology_showing_the_flow_of_information_from_DNA_to_the_phenotype._Associated_with_each_stage_is_the_corresponding_systems_biology_tool_from_genomics_to_genomics_to_metabolomics.png
- MeSH:
  - Descriptor ID: D055432.
  - Tree codes include H01.158.201.586 (biochemistry) and H01.158.273.180.599 (computational biology).
- Knowledge and platform identifiers:
  - Freebase: /m/03_pm1 (reference publication: 2013-10-28).
  - Google Knowledge Graph ID: /g/122222nt.
  - GitHub topic: "metabolomics" (reference date 2022-05-16).
- Wikipedia:
  - Title: Metabolomics.
  - Sitelink count: 26.

### Related Entities (examples)
- Stable Isotope Resolved Metabolomics (SIRM) — a specialized branch employing stable isotopes.
- Enveda — a biotechnology company listed as related (inception 2019-04-00; headquarters Boulder, United States).
- Named researchers appear in related metadata (examples in provided material include Cathy H. Wu and Daniel Domingo-Fernández).

### Bibliographic and Encyclopedia Entries
- Encyclopædia Britannica Online entries exist for "metabolomics" and "targeted metabolomics" (contributors listed include James Bain and Chris Newgard for one entry).
- JSTOR and other library-topic identifiers cite "metabolomics" as a topic.

## Schema Markup
```json
{
  "@context": "https://schema.org",
  "@type": "Thing",
  "name": "Metabolomics",
  "description": "The scientific study of chemical processes involving metabolites and the metabolome.",
  "url": "https://en.wikipedia.org/wiki/Metabolomics",
  "sameAs": [
    "https://en.wikipedia.org/wiki/Metabolomics"
  ],
  "additionalType": "academic discipline"
}

## References

1. Freebase Data Dumps. 2013
2. [metabolomics · GitHub Topics](https://github.com/topics/metabolomics)
3. [OpenAlex](https://docs.openalex.org/download-snapshot/snapshot-data-format)