# menin

> mammalian protein found in Homo sapiens

**Wikidata**: [Q1920577](https://www.wikidata.org/wiki/Q1920577)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/MEN1)  
**Source**: https://4ort.xyz/entity/menin


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O00255)
3. Q20641742
4. Freebase Data Dumps. 2013
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00255)
6. [c-Myb, Menin, GATA-3, and MLL form a dynamic transcription complex that plays a pivotal role in human T helper type 2 cell development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00255)
7. [Inactivation of menin, a Smad3-interacting protein, blocks transforming growth factor type beta signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00255)
8. [The tumor suppressor protein menin interacts with NF-kappaB proteins and inhibits NF-kappaB-mediated transactivation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00255)
9. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00255)
10. [Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locus](http://www.ebi.ac.uk/QuickGO/annotations?protein=O00255&geneProductId=UniProtKB:O00255)
11. [The 32-kilodalton subunit of replication protein A interacts with menin, the product of the MEN1 tumor suppressor gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00255)
12. [Menin interacts directly with the homeobox-containing protein Pem](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00255)
13. [Menin associates with FANCD2, a protein involved in repair of DNA damage](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00255)
14. [Menin interacts with the AP1 transcription factor JunD and represses JunD-activated transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00255)
15. [Multiple endocrine neoplasia type 1 interacts with forkhead transcription factor CHES1 in DNA damage response](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00255)
16. [Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00255)
17. [Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00255)
18. [Menin, a tumor suppressor, associates with nonmuscle myosin II-A heavy chain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00255)
19. [Menin stimulates homology-directed DNA repair](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00255)
20. [HTLV-1 bZIP factor impedes the menin tumor suppressor and upregulates JunD-mediated transcription of the hTERT gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00255)
21. [Direct binding of DNA by tumor suppressor menin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00255)
22. [Direct binding of DNA by tumor suppressor menin](http://www.ebi.ac.uk/QuickGO/annotations?protein=O00255&geneProductId=UniProtKB:O00255)
23. [Menin associates with FANCD2, a protein involved in repair of DNA damage](http://www.ebi.ac.uk/QuickGO/annotations?protein=O00255&geneProductId=UniProtKB:O00255)
24. [Menin, the product of the MEN1 gene, is a nuclear protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00255)
25. [Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00255)
26. [PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00255)
27. [PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex](http://www.ebi.ac.uk/QuickGO/annotations?protein=O00255&geneProductId=UniProtKB:O00255)
28. [Menin uncouples Elk-1, JunD and c-Jun phosphorylation from MAP kinase activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00255)
29. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O00255&geneProductId=UniProtKB:O00255)
30. [Multiple tumor suppressor pathways negatively regulate telomerase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00255)
31. [Menin suppresses osteoblast differentiation by antagonizing the AP-1 factor, JunD](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00255)
32. [Menin localizes to chromatin through an ATR-CHK1 mediated pathway after UV-induced DNA damage](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00255)
33. Ensembl Release 99
34. [OpenAlex](https://docs.openalex.org/download-snapshot/snapshot-data-format)