Menin 1
type: Thing
description: mammalian protein found in Rattus norvegicus
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P279
  value: protein
additional property: PropertyValue
  property ID: P361
  value: Menin
additional property: PropertyValue
  property ID: P637
  value: NP_062081
additional property: PropertyValue
  property ID: P637
  value: XP_006230831
additional property: PropertyValue
  property ID: P637
  value: XP_006230832
additional property: PropertyValue
  property ID: P680
  value: four-way junction DNA binding
additional property: PropertyValue
  property ID: P680
  value: Y-form DNA binding
additional property: PropertyValue
  property ID: P680
  value: molecular function
additional property: PropertyValue
  property ID: P681
  value: chromatin
additional property: PropertyValue
  property ID: P681
  value: nucleus
additional property: PropertyValue
  property ID: P681
  value: nucleoplasm
additional property: PropertyValue
  property ID: P682
  value: negative regulation of transcription by RNA polymerase II
additional property: PropertyValue
  property ID: P682
  value: MAPK cascade
additional property: PropertyValue
  property ID: P682
  value: mitotic cell cycle
additional property: PropertyValue
  property ID: P702
  value: Men1
additional property: PropertyValue
  property ID: P703
  value: brown rat
additional property: PropertyValue
  property ID: P705
  value: ENSRNOP00000028592
additional property: PropertyValue
  property ID: P705
  value: ENSRNOP00000076697
confidence:
  popularity graph score:
    score: 0.002
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 16
      unique citations norm: 0.006
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 16
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P279:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: Q9WVR8
    source count: 1
    confidence: 0.2
  P361:
    value: Q24721082
    source count: 1
    confidence: 0.2
    value label: Menin
  P637:
    value: NP_062081
    source count: 1
    confidence: 0.2
  P637:
    value: XP_006230831
    source count: 1
    confidence: 0.2
  P637:
    value: XP_006230832
    source count: 1
    confidence: 0.2
  P637:
    value: XP_006230833
    source count: 1
    confidence: 0.2
  P637:
    value: XP_006230834
    source count: 1
    confidence: 0.2
  P680:
    value: Q14911670
    source count: 1
    confidence: 0.2
    value label: four-way junction DNA binding
  P680:
    value: Q14883716
    source count: 2
    confidence: 0.4
    value label: Y-form DNA binding
  P680:
    value: Q14860489
    source count: 1
    confidence: 0.2
    value label: molecular function
  P680:
    value: Q14633858
    source count: 1
    confidence: 0.2
    value label: DNA binding
  P680:
    value: Q14817976
    source count: 2
    confidence: 0.4
    value label: chromatin binding
  P681:
    value: Q180951
    source count: 2
    confidence: 0.4
    value label: chromatin
  P681:
    value: Q40260
    source count: 5
    confidence: 1.0
    value label: nucleus
  P681:
    value: Q14817956
    source count: 1
    confidence: 0.2
    value label: nucleoplasm
  P681:
    value: Q79899
    source count: 1
    confidence: 0.2
    value label: cytoplasm
  P681:
    value: Q220599
    source count: 1
    confidence: 0.2
    value label: cytosol
  P682:
    value: Q14633878
    source count: 2
    confidence: 0.4
    value label: negative regulation of transcription by RNA polymerase II
  P682:
    value: Q14758900
    source count: 1
    confidence: 0.2
    value label: MAPK cascade
  P682:
    value: Q14763008
    source count: 1
    confidence: 0.2
    value label: mitotic cell cycle
  P682:
    value: Q14860865
    source count: 1
    confidence: 0.2
    value label: negative regulation of protein phosphorylation
  P682:
    value: Q14859914
    source count: 1
    confidence: 0.2
    value label: osteoblast development
  P702:
    value: Q24407133
    source count: 1
    confidence: 0.2
    value label: Men1
  P703:
    value: Q184224
    source count: 1
    confidence: 0.2
    value label: brown rat

value: ENSRNOP00000028592
source count: 1
confidence: 0.2

value: ENSRNOP00000076697
source count: 1
confidence: 0.2

source: GOA
stated in qid: Q28018111
retrieved: 2019-02-14

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2019-02-14

source: GOA
stated in qid: Q28018111
retrieved: 2018-01-01

source: Altered MENIN expression disrupts the MAFA differentiation pathway in insulinoma
stated in qid: Q28577962
retrieved: 2019-02-14

source: Structure and distribution of rat menin mRNA
stated in qid: Q28583443
retrieved: 2019-02-14

source: Reexpression of oncoprotein MafB in proliferative β-cells and Men1 insulinomas in mouse
stated in qid: Q28577539
retrieved: 2019-02-14

source: Cell cycle regulation of menin expression
stated in qid: Q28582170
retrieved: 2019-02-14

source: Reduction of menin expression enhances cell proliferation and is tumorigenic in intestinal epithelial cells
stated in qid: Q28579115
retrieved: 2019-02-14

source: Activin inhibits pituitary prolactin expression and cell growth through Smads, Pit-1 and menin
stated in qid: Q28564414
retrieved: 2019-02-14

source: Changes in global gene expression during in vitro decidualization of rat endometrial stromal cells
stated in qid: Q28567241
retrieved: 2019-02-14

source: Glucose-Mediated Repression of Menin Promotes Pancreatic β-Cell Proliferation
stated in qid: Q28567392
retrieved: 2019-02-14

source: Differential and complementary effects of glucose and prolactin on islet DNA synthesis and gene expression
stated in qid: Q28580527
retrieved: 2019-02-14

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2022-05-25

source: Q20641742
stated in qid: Q20641742
retrieved: 2022-03-20

source: ensembl Release 106
stated in qid: Q111699881

wikidata id: Q28559372
domain: protein
level: standard
html url: https://4ort.xyz/entity/menin-1
markdown url: https://4ort.xyz/entity/menin-1.md
facts url summary: https://4ort.xyz/entity/menin-1/facts.json
facts url standard: https://4ort.xyz/entity/menin-1/facts.json
facts url full: https://4ort.xyz/entity/menin-1/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-31T05:52:00.649542Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T14:58:40.809833+00:00Z