# Melanocortin 4 receptor

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21118676](https://www.wikidata.org/wiki/Q21118676)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/Melanocortin_4_receptor)  
**Source**: https://4ort.xyz/entity/melanocortin-4-receptor


## References

1. UniProt
2. IUPHAR/BPS Guide to PHARMACOLOGY
3. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL3301624)
4. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P32245)
5. Q20641742
6. [Swiss-Prot](http://www.uniprot.org/uniprot/P32245.txt?version=164)
7. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32245)
8. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P32245&geneProductId=UniProtKB:P32245)
9. [Novel binding motif of ACTH analogues at the melanocortin receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32245)
10. [Identification and characterization of melanocortin-4 receptor gene mutations in morbidly obese finnish children and adults](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32245)
11. [The cytosolic chaperone Hsc70 promotes traffic to the cell surface of intracellular retained melanocortin-4 receptor mutants](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32245)
12. [MRAP and MRAP2 are bidirectional regulators of the melanocortin receptor family](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32245)
13. [Morphine down-regulates melanocortin-4 receptor expression in brain regions that mediate opiate addiction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32245)
14. [Mahogunin ring finger-1 (MGRN1) E3 ubiquitin ligase inhibits signaling from melanocortin receptor by competition with Galphas](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32245)
15. [Functional analysis of the Ala67Thr polymorphism in agouti related protein associated with anorexia nervosa and leanness](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32245)
16. [Molecular cloning, expression, and gene localization of a fourth melanocortin receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32245)
17. [Functional characterization of mutations in melanocortin-4 receptor associated with human obesity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32245)
18. [Cart overexpression is the only identifiable cause of high bone mass in melanocortin 4 receptor deficiency](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32245)
19. [A frameshift mutation in MC4R associated with dominantly inherited human obesity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32245)
20. Ensembl Release 99
21. Transporter Classification database
22. [OpenAlex](https://docs.openalex.org/download-snapshot/snapshot-data-format)