# MDS1 and EVI1 complex locus

> mammalian protein found in Mus musculus

**Wikidata**: [Q21984450](https://www.wikidata.org/wiki/Q21984450)  
**Source**: https://4ort.xyz/entity/mds1-and-evi1-complex-locus-q21984450


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P14404)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14404)
5. [Identification, nuclear localization, and DNA-binding activity of the zinc finger protein encoded by the Evi-1 myeloid transforming gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14404)
6. [Oncogenic transcription factor Evi1 regulates hematopoietic stem cell proliferation through GATA-2 expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14404)
7. [A novel interaction between the proto-oncogene Evi1 and histone methyltransferases, SUV39H1 and G9a](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14404)
8. [Myeloid transforming protein Evi1 interacts with methyl-CpG binding domain protein 3 and inhibits in vitro histone deacetylation by Mbd3/Mi-2/NuRD](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14404)
9. [Ecotopic viral integration site 1 (EVI1) regulates multiple cellular processes important for cancer and is a synergistic partner for FOS protein in invasive tumors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14404)
10. [Zinc fingers 1-7 of EVI1 fail to bind to the GATA motif by itself but require the core site GACAAGATA for binding](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14404)
11. [Pbx1 is a downstream target of Evi-1 in hematopoietic stem/progenitors and leukemic cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14404)
12. [Prdm3 and Prdm16 are H3K9me1 methyltransferases required for mammalian heterochromatin integrity.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14404)
13. [Mutation at the Evi1 locus in Junbo mice causes susceptibility to otitis media](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14404)
14. [Vesicoureteral Reflux and Other Urinary Tract Malformations in Mice Compound Heterozygous for Pax2 and Emx2](http://www.ebi.ac.uk/QuickGO/annotations?protein=P14404&geneProductId=UniProtKB:P14404)
15. [Prdm16 is required for the maintenance of brown adipocyte identity and function in adult mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14404)
16. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P14404&geneProductId=UniProtKB:P14404)
17. [Vesicoureteral Reflux and Other Urinary Tract Malformations in Mice Compound Heterozygous for Pax2 and Emx2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14404)
18. ensembl Release 106