# MCM DNA helicase complex subunit MCM2 YBL023C

> fungal protein found in Saccharomyces cerevisiae S288c

**Wikidata**: [Q27553071](https://www.wikidata.org/wiki/Q27553071)  
**Source**: https://4ort.xyz/entity/mcm-dna-helicase-complex-subunit-mcm2-ybl023c


## References

1. UniProt
2. Q20641742
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P29469)
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29469)
5. [Differences in the Single-stranded DNA Binding Activities of MCM2-7 and MCM467](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29469)
6. [The B2 element of the Saccharomyces cerevisiae ARS1 origin of replication requires specific sequences to facilitate pre-RC formation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29469)
7. [Reconstitution of Saccharomyces cerevisiae prereplicative complex assembly in vitro](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29469)
8. [Mcm10 and the MCM2-7 complex interact to initiate DNA synthesis and to release replication factors from origins.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29469)
9. [The Mcm2-7 Complex Has In Vitro Helicase Activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29469)
10. [Mcm10 associates with the loaded DNA helicase at replication origins and defines a novel step in its activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29469)
11. [A Ctf4 trimer couples the CMG helicase to DNA polymerase α in the eukaryotic replisome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29469)
12. [A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replication](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29469)
13. [Structure of the eukaryotic MCM complex at 3.8 Å](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29469)
14. [High-Quality Binary Protein Interaction Map of the Yeast Interactome Network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29469)
15. [Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29469)
16. [Concerted Loading of Mcm2–7 Double Hexamers around DNA during DNA Replication Origin Licensing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29469)
17. [Cryo-EM structure of a helicase loading intermediate containing ORC–Cdc6–Cdt1–MCM2-7 bound to DNA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29469)
18. [SCFDia2 regulates DNA replication forks during S‐phase in budding yeast](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29469)
19. [Identification of Cdc6 protein domains involved in interaction with Mcm2 protein and Cdc4 protein in budding yeast cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29469)
20. [A new MCM modification cycle regulates DNA replication initiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29469)
21. [Reconstitution of the Mcm2-7p Heterohexamer, Subunit Arrangement, and ATP Site Architecture](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29469)
22. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29469)
23. [Formation of a Preinitiation Complex by S-phase Cyclin CDK-Dependent Loading of Cdc45p onto Chromatin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29469)
24. [Cell cycle-regulated nuclear localization of MCM2 and MCM3, which are required for the initiation of DNA synthesis at chromosomal replication origins in yeast.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P29469&geneProductId=UniProtKB:P29469)
25. [Clb/Cdc28 kinases promote nuclear export of the replication initiator proteins Mcm2–7](http://www.ebi.ac.uk/QuickGO/annotations?protein=P29469&geneProductId=UniProtKB:P29469)
26. [GINS maintains association of Cdc45 with MCM in replisome progression complexes at eukaryotic DNA replication forks](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29469)
27. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P29469&geneProductId=UniProtKB:P29469)
28. [Components and Dynamics of DNA Replication Complexes in S. cerevisiae: Redistribution of MCM Proteins and Cdc45p during S Phase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29469)
29. [The architecture of a eukaryotic replisome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29469)
30. [Clb/Cdc28 kinases promote nuclear export of the replication initiator proteins Mcm2–7](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29469)
31. [Cell cycle-regulated nuclear localization of MCM2 and MCM3, which are required for the initiation of DNA synthesis at chromosomal replication origins in yeast.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29469)
32. [Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29469)
33. [Break-induced replication requires all essential DNA replication factors except those specific for pre-RC assembly](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29469)
34. [Mcm2 phosphorylation and the response to replicative stress](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29469)
35. [Mcm2 is a target of regulation by Cdc7–Dbf4 during the initiation of DNA synthesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29469)
36. [Uninterrupted MCM2-7 Function Required for DNA Replication Fork Progression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29469)
37. ensembl Release 106