# Matrix metallopeptidase 9

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21105703](https://www.wikidata.org/wiki/Q21105703)  
**Source**: https://4ort.xyz/entity/matrix-metallopeptidase-9-q21105703


## References

1. UniProt
2. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL440498)
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P14780)
4. Q20641742
5. [SV40-transformed human lung fibroblasts secrete a 92-kDa type IV collagenase which is identical to that secreted by normal human macrophages](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14780)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14780)
7. [The subject of epidemiology](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14780)
8. [Extracellular matrix protein 1 inhibits the activity of matrix metalloproteinase 9 through high-affinity protein/protein interactions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14780)
9. [Plasma levels of the MMP-9:TIMP-1 complex as prognostic biomarker in breast cancer: a retrospective study](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14780)
10. [Meprins process matrix metalloproteinase-9 (MMP-9)/gelatinase B and enhance the activation kinetics by MMP-3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14780)
11. [SCUBE3 is an endogenous TGF-β receptor ligand and regulates the epithelial-mesenchymal transition in lung cancer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14780)
12. [In vitro reconstitution of complexes between pro‐matrix metalloproteinase‐9 and the proteoglycans serglycin and versican](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14780)
13. [Human neutrophils uniquely release TIMP-free MMP-9 to provide a potent catalytic stimulator of angiogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14780)
14. [Insights into the structure and domain flexibility of full-length pro-matrix metalloproteinase-9/gelatinase B.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14780)
15. [L-Plastin Nanobodies Perturb Matrix Degradation, Podosome Formation, Stability and Lifetime in THP-1 Macrophages](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14780)
16. [Cadmium induces matrix metalloproteinase-9 expression via ROS-dependent EGFR, NF-кB, and AP-1 pathways in human endothelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14780)
17. [Increased alpha-synuclein aggregation following limited cleavage by certain matrix metalloproteinases](http://www.ebi.ac.uk/QuickGO/annotations?protein=P14780&geneProductId=UniProtKB:P14780)
18. [Chymase cleavage of stem cell factor yields a bioactive, soluble product](http://www.ebi.ac.uk/QuickGO/annotations?protein=P14780&geneProductId=UniProtKB:P14780)
19. [Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligand](http://www.ebi.ac.uk/QuickGO/annotations?protein=P14780&geneProductId=UniProtKB:P14780)
20. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P14780&geneProductId=UniProtKB:P14780)
21. [Ligand binding and calcium influx induce distinct ectodomain/gamma-secretase-processing pathways of EphB2 receptor](http://www.ebi.ac.uk/QuickGO/annotations?protein=P14780&geneProductId=UniProtKB:P14780)
22. [Trypsin-2 degrades human type II collagen and is expressed and activated in mesenchymally transformed rheumatoid arthritis synovitis tissue](http://www.ebi.ac.uk/QuickGO/annotations?protein=P14780&geneProductId=UniProtKB:P14780)
23. [Cyclic Nucleotide-Gated Channel Subunit Glycosylation Regulates Matrix Metalloproteinase-Dependent Changes in Channel Gating](http://www.ebi.ac.uk/QuickGO/annotations?protein=P14780&geneProductId=UniProtKB:P14780)
24. [SV40-transformed human lung fibroblasts secrete a 92-kDa type IV collagenase which is identical to that secreted by normal human macrophages](http://www.ebi.ac.uk/QuickGO/annotations?protein=P14780&geneProductId=UniProtKB:P14780)
25. [Regulation of matrix metalloproteinase-9 and inhibition of tumor invasion by the membrane-anchored glycoprotein RECK](http://www.ebi.ac.uk/QuickGO/annotations?protein=P14780&geneProductId=UniProtKB:P14780)
26. [Cyclic Nucleotide-Gated Channel Subunit Glycosylation Regulates Matrix Metalloproteinase-Dependent Changes in Channel Gating](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14780)
27. [Trypsin-2 degrades human type II collagen and is expressed and activated in mesenchymally transformed rheumatoid arthritis synovitis tissue](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14780)
28. [Regulation of matrix metalloproteinase-9 and inhibition of tumor invasion by the membrane-anchored glycoprotein RECK](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14780)
29. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14780)
30. [Increased alpha-synuclein aggregation following limited cleavage by certain matrix metalloproteinases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14780)
31. [Ligand binding and calcium influx induce distinct ectodomain/gamma-secretase-processing pathways of EphB2 receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14780)
32. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P14780&geneProductId=UniProtKB:P14780)
33. [Proteomic analysis of podocyte exosome-enriched fraction from normal human urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P14780&geneProductId=UniProtKB:P14780)
34. [Human neutrophils secrete bioactive paucimannosidic proteins from azurophilic granules into pathogen-infected sputum](http://www.ebi.ac.uk/QuickGO/annotations?protein=P14780&geneProductId=UniProtKB:P14780)
35. [L-Plastin Nanobodies Perturb Matrix Degradation, Podosome Formation, Stability and Lifetime in THP-1 Macrophages](http://www.ebi.ac.uk/QuickGO/annotations?protein=P14780&geneProductId=UniProtKB:P14780)
36. [Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins](http://www.ebi.ac.uk/QuickGO/annotations?protein=P14780&geneProductId=UniProtKB:P14780)
37. [Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14780)
38. [Human neutrophils secrete bioactive paucimannosidic proteins from azurophilic granules into pathogen-infected sputum](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14780)
39. [Proteomic characterization of human multiple myeloma bone marrow extracellular matrix.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14780)
40. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14780)
41. [Apoptosis Induced by Knockdown of uPAR and MMP-9 is Mediated by Inactivation of EGFR/STAT3 Signaling in Medulloblastoma](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14780)
42. [Regulation of endodermal differentiation of human embryonic stem cells through integrin-ECM interactions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14780)
43. [Proteolytic cleavage of extracellular secreted {alpha}-synuclein via matrix metalloproteinases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14780)
44. [Role of ADAM-9 disintegrin-cysteine-rich domains in human keratinocyte migration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14780)
45. [SM22alpha-targeted deletion of bone morphogenetic protein receptor 1A in mice impairs cardiac and vascular development, and influences organogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14780)
46. [DDRGK1 Regulates NF-κB Activity by Modulating IκBα Stability](http://www.ebi.ac.uk/QuickGO/annotations?protein=P14780&geneProductId=UniProtKB:P14780)
47. [DDRGK1 Regulates NF-κB Activity by Modulating IκBα Stability](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14780)
48. [miR-204-5p acts as a tumor suppressor by targeting matrix metalloproteinases-9 and B-cell lymphoma-2 in malignant melanoma](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14780)
49. [Matrix metalloproteinase-8 plays a pivotal role in neuroinflammation by modulating TNF-α activation.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14780)
50. Ensembl Release 99