# Matrix metallopeptidase 14

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21109573](https://www.wikidata.org/wiki/Q21109573)  
**Source**: https://4ort.xyz/entity/matrix-metallopeptidase-14


## References

1. UniProt
2. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL440498)
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P50281)
4. Q20641742
5. [A matrix metalloproteinase expressed on the surface of invasive tumour cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50281)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50281)
7. [MT1-MMP cleaves Dll1 to negatively regulate Notch signalling to maintain normal B-cell development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50281)
8. [GI24 enhances tumor invasiveness by regulating cell surface membrane-type 1 matrix metalloproteinase.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50281)
9. [Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein-1 is a new member of the Cupin superfamily. A possible multifunctional protein acting as an invasion suppressor down-regulated in tumors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50281)
10. [BST-2 binding with cellular MT1-MMP blocks cell growth and migration via decreasing MMP2 activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50281)
11. [Furin Functions as a Nonproteolytic Chaperone for Matrix Metalloproteinase-28: MMP-28 Propeptide Sequence Requirement](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50281)
12. [Sphingosine-1-phosphate induces the association of membrane-type 1 matrix metalloproteinase with p130Cas in endothelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50281)
13. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50281)
14. [Detection of a latent soluble form of membrane type 1 matrix metalloprotease bound with tissue inhibitor of matrix metalloproteinases-2 in periprosthetic tissues and fluids from loose arthroplasty endoprostheses](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50281)
15. [Golgi reassembly stacking protein 55 interacts with membrane-type (MT) 1-matrix metalloprotease (MMP) and furin and plays a role in the activation of the MT1-MMP zymogen](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50281)
16. [LIM kinase1 modulates function of membrane type matrix metalloproteinase 1: implication in invasion of prostate cancer cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50281)
17. [FGF receptor-4 (FGFR4) polymorphism acts as an activity switch of a membrane type 1 matrix metalloproteinase-FGFR4 complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50281)
18. [Lumican: a new inhibitor of matrix metalloproteinase-14 activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50281)
19. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P50281&geneProductId=UniProtKB:P50281)
20. [A matrix metalloproteinase expressed on the surface of invasive tumour cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P50281&geneProductId=UniProtKB:P50281)
21. [The low density lipoprotein receptor-related protein LRP is regulated by membrane type-1 matrix metalloproteinase (MT1-MMP) proteolysis in malignant cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50281)
22. [Prion Fragment Peptides Are Digested with Membrane Type Matrix Metalloproteinases and Acquire Enzyme Resistance through Cu2+-Binding](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50281)
23. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50281)
24. [Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein-1 is a new member of the Cupin superfamily. A possible multifunctional protein acting as an invasion suppressor down-regulated in tumors](http://www.ebi.ac.uk/QuickGO/annotations?protein=P50281&geneProductId=UniProtKB:P50281)
25. [MT1-MMP cleaves Dll1 to negatively regulate Notch signalling to maintain normal B-cell development](http://www.ebi.ac.uk/QuickGO/annotations?protein=P50281&geneProductId=UniProtKB:P50281)
26. [GI24 enhances tumor invasiveness by regulating cell surface membrane-type 1 matrix metalloproteinase.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P50281&geneProductId=UniProtKB:P50281)
27. [BST-2 binding with cellular MT1-MMP blocks cell growth and migration via decreasing MMP2 activity](http://www.ebi.ac.uk/QuickGO/annotations?protein=P50281&geneProductId=UniProtKB:P50281)
28. [FGF receptor-4 (FGFR4) polymorphism acts as an activity switch of a membrane type 1 matrix metalloproteinase-FGFR4 complex](http://www.ebi.ac.uk/QuickGO/annotations?protein=P50281&geneProductId=UniProtKB:P50281)
29. [LIM kinase1 modulates function of membrane type matrix metalloproteinase 1: implication in invasion of prostate cancer cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P50281&geneProductId=UniProtKB:P50281)
30. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?protein=P50281&geneProductId=UniProtKB:P50281)
31. [Detection of a latent soluble form of membrane type 1 matrix metalloprotease bound with tissue inhibitor of matrix metalloproteinases-2 in periprosthetic tissues and fluids from loose arthroplasty endoprostheses](http://www.ebi.ac.uk/QuickGO/annotations?protein=P50281&geneProductId=UniProtKB:P50281)
32. [Golgi reassembly stacking protein 55 interacts with membrane-type (MT) 1-matrix metalloprotease (MMP) and furin and plays a role in the activation of the MT1-MMP zymogen](http://www.ebi.ac.uk/QuickGO/annotations?protein=P50281&geneProductId=UniProtKB:P50281)
33. [Sphingosine-1-phosphate induces the association of membrane-type 1 matrix metalloproteinase with p130Cas in endothelial cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P50281&geneProductId=UniProtKB:P50281)
34. [Lumican: a new inhibitor of matrix metalloproteinase-14 activity](http://www.ebi.ac.uk/QuickGO/annotations?protein=P50281&geneProductId=UniProtKB:P50281)
35. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=P50281&geneProductId=UniProtKB:P50281)
36. [The low density lipoprotein receptor-related protein LRP is regulated by membrane type-1 matrix metalloproteinase (MT1-MMP) proteolysis in malignant cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P50281&geneProductId=UniProtKB:P50281)
37. [Prion Fragment Peptides Are Digested with Membrane Type Matrix Metalloproteinases and Acquire Enzyme Resistance through Cu2+-Binding](http://www.ebi.ac.uk/QuickGO/annotations?protein=P50281&geneProductId=UniProtKB:P50281)
38. [Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P50281&geneProductId=UniProtKB:P50281)
39. [Involvement of syntaxin 4 in the transport of membrane-type 1 matrix metalloproteinase to the plasma membrane in human gastric epithelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50281)
40. [CLASPs link focal-adhesion-associated microtubule capture to localized exocytosis and adhesion site turnover](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50281)
41. [A new transcriptional role for matrix metalloproteinase-12 in antiviral immunity](http://www.ebi.ac.uk/QuickGO/annotations?protein=P50281&geneProductId=UniProtKB:P50281)
42. [A new transcriptional role for matrix metalloproteinase-12 in antiviral immunity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50281)
43. [Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50281)
44. [Regulation of endodermal differentiation of human embryonic stem cells through integrin-ECM interactions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50281)
45. [Proteolytic cleavage of extracellular secreted {alpha}-synuclein via matrix metalloproteinases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50281)
46. Ensembl Release 99
47. Transporter Classification database